ANGPTL3

(redirected from angiopoietin-like 3)

ANGPTL3

A gene on chromosome 1p31.1-p22.3 that encodes angiopoietin-like protein 3, which is expressed primarily in the liver.

Molecular pathology
ANGPTL3 mutations are associated with familial hypobetalipoproteinaemia type 2.
References in periodicals archive ?
In this study, subjects with elevated triglycerides achieved substantial and statistically significant mean reductions in angiopoietin-like 3 (ANGPTL3), triglycerides and LDL-cholesterol of up to 83 percent, 66 percent, and 35 percent, respectively.
ISIS-ANGPTL3Rx, which is an antisense drug targeting angiopoietin-like 3 protein (ANGPTL3) and an independent risk factor for cardiovascular disease, is designed to act as a broad dyslipidemia agent, according to the company.