angiopoietin


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angiopoietin

(an″jē-ō-poy-ē′tĭn; -poy′ĕ-tĭn) [ angio- + -poiet(ic) + -in]
Any of several genes (or the proteins they encode) that stimulate new blood vessel formation. The proteins encoded by angiopoietin are found in healthy cardiac endothelium and in diseased tissues such as arthritic joints and malignant tumors.
References in periodicals archive ?
Angiopoietin (Ang)-1 and Ang-2 improves angiogenesis, promoting vascular maturation and diminution of vascular permeability.
13],[14],[15] Other cytokines, adhesion molecules, and glycoproteins, including transforming growth factor-[sz], fibroblast growth factor, platelet-derived growth factor, angiopoietin, epidermal growth factor, and ephrins, are vital for the occurrence, development, and recurrence of cAVMs.
B AP-1 1/2 Lindane BPA DBP and DEHP 2/3 Ras, Raf-1, ERK FAK CASP-9 - Bad MMP1 and MMP2, integrins, angiopoietin (Ang 1) 2 CASP-9 2 hTERT protein expression p21 2/3 CAMs Level of Prototype substances information: associated with early key Early key events events 1 DES (Gibson and Saunders, 2014) TCDD (Murray et al.
Angiopoietin like protein 4 expression is decreased in activated macrophages.
Sundberg, "The influence of physical training on the angiopoietin and VEGF-A systems in human skeletal muscle," Journal of Applied Physiology, vol.
It is expected to induce angiogenesis through release of vascular endothelial growth factors, epithelial growth factors, angiopoietin and improve the perfusion and help the repair and regeneration of the ischemic muscle tissue.
Androgens modulate the balance between VEGF and angiopoietin expression in prostate epithelial and smooth muscle cells.
Trebananib (formally known as AMG 386; Amgen) is a first-in-class peptide-Fc fusion protein (or peptibody) that targets angiogenesis (the growth of new blood vessels into cancerous tumors) by inhibiting the binding of both angiopoietin 1 and 2 to the Tie2 receptor.
Vascular endothelial growth factor (VEGF) and angiopoietin (Ang) are two important factors required for angiogenesis.
Colon cancer cells treated with grape seed proanthocyanidins in the laboratory showed inhibition of the vascular endothelial growth factor (VEGF) and angiopoietin 1 (Ang1), thereby blocking blood supply to tumor cells.
17,18) Other cytokines released include interleukin 8 (IL-8), angiopoietin, and metalloproteases (MMP) 1, 2, and 9.
Algunos ejemplos son: Angiopoietin (Ang), Bone morphogenetic proteins (BMPs), Epidermal growth factor (EGF), Erythropoietin (EPO), Fibroblast growth factor (FGF), Growth differentiation factor-9 (GDF9), Insulin-like growth factor (IGF), Interleukines (IL), Migrationstimulating factor, Myostatin (GDF-8), Nerve growth factor (NGF) and other neurotrophins, Placental growth factor (PlGF), Platelet-derived growth factor (PDGF), Transforming growth factor alpha (TGF-[alfa]), Transforming growth factor beta(TGF-[beta]), Tumor-necrosis-factor-alpha (TNF-[alfa]), Vascular endothelial growth factor (VEGF) .