Relating to angiopathy.
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Prior to 1960 three main theories existed as to the pathogenesis of diabetic hearing impairment and vestibular dysfunction, namely a neuropathy, an angiopathy and a combination of the two (Taylor, 1978), whereas, after that date the vast majority of workers agree that the primary lesion is angiopathic (Jorgensen, 1961).
The raised levels of glycoproteins in diabetics may also be an indicator of angiopathic complications (Konukoglu et al.
Technologists should be especially alert to fragmented forms indicating angiopathic hemolytic anemias--notably those associated with disseminated intravascular coagulation.
DISCUSSION: Hemolytic uremic syndrome (HUS) is defined by the triad of micro angiopathic hemolytic anemia, thrombocytopenia and renal impairment.
During diabetes, utilization of glucose by insulin independent pathways leads to the synthesis of glycoprotein which may be a predictor of angiopathic complications (Wiese et al.
The cause of jaundice is due to increased intravascular hemolysis of parasitized erythrocyte, hepatic dysfunction and rarely micro angiopathic hemolysis due to disseminated intravascular coagulation.
3) The factors that contribute AKI due to snake bite are Direct cytotoxicity, Bleeding, Hypotension, Circulatory collapse, Intravascular hemolysis, Disseminated Intravascular Coagulation and Micro Angiopathic Hemolytic Anemia (MAHA).