angiomyofibroblastoma

angiomyofibroblastoma

(an'gē-ō-mī'ō-fī'brō-blas-tō'mă),
Benign well-circumscribed tumor composed of blood vessels, myofibroblastic cells, and fat cells, usually found in the pelviperineal region of women.

angiomyofibroblastoma

A benign, well-circumscribed, < 3 cm tumour, often of vulvar soft tissue, which affects young to middle-aged women.

DiffDx
Aggressive angiomyxoma, cellular angiofibroma.
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References in periodicals archive ?
"Angiomyxoid tumor with an intermediate feature between cellular angiofibroma and angiomyofibroblastoma in the male inguinal region." Int J Urol.
Angiomyofibroblastomalike tumour of the male genital tract: Analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma.
Tumor regression has been seen in angiomyofibroblastoma [8].
Vulvar angiomyxoma, aggressive angiomyxoma and angiomyofibroblastoma: an immunohistochemical and ultrastructural study.
Sato, "Angiomyofibroblastoma of the female urethra," International Journal of Urology, vol.
The immune-phenotype of angiomyofibroblastoma AMF is not distinct but most cases are desmin positive and [alpha] smooth muscle actin negative.
Aggressive angiomyxoma: reappraisal of its relationship to angiomyofibroblastoma in a series of 16 cases.
Differential diagnosis Features Angiomyolipoma Collection of fat cells with muscular arteriole Angiomyofibroblastoma Loose, myxoid, and fibroblastic element Juvenile nasopharyngeal Cornified to the nasopharynx angiofibroma and histopathologically shows homogenous fibroplasias with immature collagen, and sinus-like vascular channels Solitary fibrous tumors Do not exhibit prominent vascular elements Spindle cell lipoma Adipocytes intimately interspersed with spindle cells Pyogenic granuloma Large thin-walled vessels in a loose connective tissue stroma infiltrated throughout by leukocytes
Ceyhan, "Angiomyofibroblastoma of the vulva: A rare but distinct entity," Acta Obstetricia et Gynecologica Scandinavica, vol.
Hamartoma, lymphadenoma, angiomyofibroblastoma, cellular angiofibroma, sarcomas, angiomyxoma and dermatofibrosarcoma protuberans are other differential diagnosis.
Normal vulvar tissue and different lesions of vulva have been surveyed for hormonal milieu receptors such as vulvar cancers, Cavernous lymphangiomas, angiomyofibroblastoma, angiomyxoma, indicating ER and PR importance in disease pathogenesis (16, 17, 18, 19) the positivity rate for ER in normal vulvar tissue varies from 33-100% (20) and it's also positive in most of CA lesions and normal vaginal epithelium (5).
Clinically and morphologically, cellular angiofibroma can simulate other benign tumours like leiomyoma, angiomyofibroblastoma, spindle cell lipoma and perineurioma (1, 5).