angiolymphoid hyperplasia with eosinophilia

Also found in: Acronyms.

an·gi·o·lym·phoid hy·per·pla·si·a with e·o·sin·o·phil·i·a

solitary or multiple small benign cutaneous erythematous nodules, occurring mainly on the head and neck in young adults, characterized by dermal proliferation of blood vessels with vacuolated histiocytoid endothelial cells and with a varied infiltrate of eosinophils, lymphocytes which may form follicles, and histiocytes.
Synonym(s): Kimura disease

angiolymphoid hyperplasia with eosinophilia

An uncommon idiopathic condition with some features of Kimura disease, which presents in adults as one or more red-blue papules, plaques, or nodules in the head and neck, less commonly in the hands, shoulders, and elsewhere. It is unknown whether it is neoplastic or reactive.
Prognosis ALHE is clinically benign but persistent and treatment is refractory.


Tetsuji, 20th century Japanese pathologist.
Kimura disease - solitary or multiple small benign cutaneous erythematous nodules. Synonym(s): angiolymphoid hyperplasia with eosinophilia
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References in periodicals archive ?
A Long-Term Follow-up of Angiolymphoid Hyperplasia with Eosinophilia Treated by Corticosteroids: When a Traditional Therapy is Still Up-to-Date.
Angiolymphoid hyperplasia with eosinophilia mimicking multiple cylindromas: a rare case report.
Angiolymphoid hyperplasia with eosinophilia that was possibly induced by vaccination in a child.
Angiolymphoid hyperplasia with eosinophilia presenting as an axillary artery aneurysm.
Angiolymphoid hyperplasia with eosinophilia on penis in HIV-positive patient.
A rare case of angiolymphoid hyperplasia with eosinophilia in the submental region.
Kimura's disease: a clinicopathological study of 21 cases and its distinction from angiolymphoid hyperplasia with eosinophilia.
Although other names have been given to ALHE/EH, such as histiocytoid hemangioma, angiomatous nodule, pseudopyogenic granuloma, and inflammatory angiomatous nodule, (3,4) angiolymphoid hyperplasia with eosinophilia and epithelioid hemangioma remain the current unanimously accepted terms for this entity.
Angiolymphoid hyperplasia with eosinophilia (Kimura's disease): a case with dermal lesions in the knee region and a popliteal arteriovenous fistula.
Polymerase chain reaction (PCR) for human herpes virus 8 and heteroduplex PCR for clonality assessment in angiolymphoid hyperplasia with eosinophilia and Kimura's disease.
Angiolymphoid hyperplasia with eosinophilia :successful treatment with indomethacin farnesil.
Table 1 Differences between angiolymphoid hyperplasia with eosinophilia and Kimura's disease.