angiolymphoid hyperplasia with eosinophilia

(redirected from angiolymphoid hyperplasia)

an·gi·o·lym·phoid hy·per·pla·si·a with e·o·sin·o·phil·i·a

solitary or multiple small benign cutaneous erythematous nodules, occurring mainly on the head and neck in young adults, characterized by dermal proliferation of blood vessels with vacuolated histiocytoid endothelial cells and with a varied infiltrate of eosinophils, lymphocytes which may form follicles, and histiocytes.
Synonym(s): Kimura disease
Farlex Partner Medical Dictionary © Farlex 2012

angiolymphoid hyperplasia with eosinophilia

An uncommon idiopathic condition with some features of Kimura disease, which presents in adults as one or more red-blue papules, plaques, or nodules in the head and neck, less commonly in the hands, shoulders, and elsewhere. It is unknown whether it is neoplastic or reactive.
Prognosis ALHE is clinically benign but persistent and treatment is refractory.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Tetsuji, 20th century Japanese pathologist.
Kimura disease - solitary or multiple small benign cutaneous erythematous nodules. Synonym(s): angiolymphoid hyperplasia with eosinophilia
Medical Eponyms © Farlex 2012
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References in periodicals archive ?
The differential diagnosis of EAF is broad and includes reactive conditions (granulomatosis with polyangiitis, Churg-Strauss syndrome, Kimura disease, angiolymphoid hyperplasia with eosinophilia, granuloma faciale, erythema elevatum diutinum), and neoplastic lesions (angiofibroma, schwannoma, fibroma, fibromatosis).
Kimura's disease: a clinico-pathological study of 21 cases and its distinction from angiolymphoid hyperplasia with eosinophilia.
Based on the history, clinical examination, and histopathology, the patient was diagnosed with angiolymphoid hyperplasia with eosinophilia (ALHE).
Clinically, ALMs must be differentiated from other benign tumors of the auricle, namely, hemangiomas, glomus tumors, epidermoid cysts, auricular pseudocysts, angiolymphoid hyperplasia with eosinophilia, and neuro(fibro)mas.
Background and Objective: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign, vasoproliferative entity of unknown etiology.
Angiolymphoid hyperplasia with eosinophilia (AHE) has an unknown pathogenesis but is considered a reactive phenomenon, possibly in response to or in association with an underlying vascular malformation.
Angiolymphoid hyperplasia with eosinophilia (ALHE), sometimes called epithelioid hemangioma, is a benign vascular tumor.
Angiolymphoid hyperplasia -- with eosinophilia (ALHE) Cat-scratch disease Nodes often show central necrosis.
KD can be confused clinically and histologically with angiolymphoid hyperplasia with eosinophilia (ALHE), also known as epitheloid hemangioma, which is a rare but distinctive vascular tumor typically occurring in women.
Observations concerning the pathogenesis of epithelioid hemangioma (angiolymphoid hyperplasia).
Wells and Whimster first reported it as angiolymphoid hyperplasia with eosinophilia (ALHE) in 1969 and Rosai et al.
It has been implicated that HHV-8 may be associated with some human diseases including primary effusion lymphoma, a rare subtype of B-cell non-Hodgkin's lymphoma (NHL) [3], multicentric Castleman disease [4], angiosarcoma [5], angiolymphoid hyperplasia with eosinophilia [6], sarcoidosis [7], squamous cell carcinoma [8], pityriasis rosea [9], and multiple myeloma (MM) [10].