Background and Objective:
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign, vasoproliferative entity of unknown etiology.
Angiolymphoid hyperplasia with eosinophilia (AHE) has an unknown pathogenesis but is considered a reactive phenomenon, possibly in response to or in association with an underlying vascular malformation.
Angiolymphoid hyperplasia with eosinophilia (ALHE), sometimes called epithelioid hemangioma, is a benign vascular tumor.
Differential diagnosis on imaging would include tuberculosis, lymphoma, metastatic adenopathy, primary parotid tumors,
angiolymphoid hyperplasia with eosinophilia (ALHE), and cat-scratch disease [Table 2].
KD can be confused clinically and histologically with
angiolymphoid hyperplasia with eosinophilia (ALHE), also known as epitheloid hemangioma, which is a rare but distinctive vascular tumor typically occurring in women.
Angiolymphoid hyperplasia with eosinophilia (ALHE), also named epithelioid hemangioma (EH), is an inflamed vascular tumefaction of uncertain pathogenesis, characterized by proliferation of histiocytoid endothelial cells with prominent lymphocytic and eosinophilic infiltration.
1,2] First described in 1969 as superficial
angiolymphoid hyperplasia with eosinophilia, the lesion is microscopically typified by well-formed capillary-sized vessels, epithelial-like endothelial cells with large nucleoli and prominent nucleoli, absent nuclear atypia, and often secondary inflammatory infiltrate.
Kimura's disease: a clinico-pathological study of 21 cases and its distinction from
angiolymphoid hyperplasia with eosinophilia.
Histologically it should be differentiated with
Angiolymphoid hyperplasia, Kaposi sarcoma, Dermatofibrosarcoma protruberans Surgical excision of lesions is first line therapy.
Angiolymphoid hyperplasia with eosinophilia, first described by Wells and Whimster in 1969, is a rare benign vascular tumor.
The differential diagnosis of Kimura disease includes such entities as eosinophilic granuloma, Mikulicz disease, acute nonlymphocytic leukemia, Hodgkin disease, follicular lymphoma, angioimmunoblastic lymphadenopathy, and
angiolymphoid hyperplasia with eosinophilia.
Unilateral
angiolymphoid hyperplasia with eosinophilia involving the left arm and hand.
