angiokeratoma


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angiokeratoma

 [an″je-o-ker″ah-to´mah]
a dermatosis marked by telangiectasia with secondary epithelial changes, including acanthosis and hyperkeratosis.
 Facial rash of angiokeratoma in a male with tuberous sclerosis. From Mueller and Young, 2001.
angiokeratoma cor´poris diffu´sum an inborn error of metabolism of glycolipids characterized by purpuric skin lesions (angiokeratomas); see also fabry's disease.

an·gi·o·ker·a·to·ma

(an'jē-ō-ker'ă-tō'mă),
A superficial, intradermal, capillary-acquired telangiectasis, with wartlike hyperkeratosis and acanthosis.
[angio- + G. keras, horn, + -ōma, tumor]

angiokeratoma

(ăn′jē-ō-kĕr′ə-tō′mə)
n.
An intradermal hemangioma covered by a wartlike thickening of the horny layer of the epidermis.

angiokeratoma

Any of a group of vascular ectasias of the papillary dermis, which may produce papillomatosis, acanthosis, and hyperkeratosis of the epidermis, which are more common in women (female:male ratio, 3:1) and on the leg. Of the 8 types, Mibelli described an angiokeratoma affecting the fingers and toes and Fabry reported angiokeratoma circumscriptum as a localised lesion on the leg or trunk. Angiokeratomas are clinically important because they clinically mimic melanoma.

an·gi·o·ker·a·to·ma

(an'jē-ō-ker-ă-tō'mă)
A superficial capillary telangiectasis, over which wartlike hyperkeratosis and acanthosis appear.
Synonym(s): telangiectatic wart.
[angio- + G. keras, horn, + -ōma, tumor]

an·gi·o·ker·a·to·ma

(an'jē-ō-ker-ă-tō'mă)
Superficial, intradermal, capillary-acquired telangiectasis, with hyperkeratosis and acanthosis.
[angio- + G. keras, horn, + -ōma, tumor]
References in periodicals archive ?
Fabry disease affects young people and can have monosymptomatic courses, which only involve CNS without any medical history of other classic Fabry symptoms such as angiokeratoma, cornea veriticillata, or heart and kidney disease.
A cutaneous hemangioma is a benign neoplasm (growth) on the skin that looks a lot like a blood blister (angiokeratoma).
Impaired glycosphingolipid metabolism leads to systemic lysosomal globotriaosylceramide accumulation with multiorgan systemic involvement and complex clinical presentation: acroparesthesias, angiokeratoma, hypohidrosis, corneal and lenticular opacities, gastrointestinal and endocrine abnormalities, renal impairment, and neural and cardiovascular disease [1, 2].
This subtype is characterized by the presence of myoclonus (a sudden and involuntary jerking of a muscle or group of muscles), ataxia, angiokeratoma (a skin condition manifested by clusters of dilated blood vessels, thickened skin, and warty growths), mental retardation, and long survival [8].
In a large retrospective case series, various skin abnormalities such as follicular papules, comedones, hypertrophic pilosebaceous units, angiokeratoma of Fordyce, leucoderma macules, and haemangiomas have been shown to be associated with NLCS.
Angiokeratoma, purple papules on upper thighs and mucosal areas, is a typical but not specific symptom.
Our patient does not have any major characteristics of Fabry disease, but she presented with major depression and angiokeratoma besides she had heterozygote mutation.
Background: Angiokeratoma of fordyce occurring over on the vulva is a rare condition.
Some patients may have rash in Scrotum, angiokeratoma and this cannot be diagnosed unless one examines the patients carefully.
Angiokeratoma. Angiokeratomas are vascular tumours consisting of numerous ectatic blood vessels in the superficial dermis.
The clinical differential diagnosis for vulvar syringoma is broad and should exclude such diseases as epidermal cyst, steatocystoma multiplex, lymphangioma circumstriptum, chronic lichen simplex, angiokeratoma in Fox-Fordyce disease, senile angioma, condyloma acuminatum, candidiasis, scabies, pediculosis, allergic and irritant contact dermatitis, psoriasis and lichen sclerosus et atrophicus (2, 7, 8, 19-21).
Angiokeratoma ectasia of blood vessel were seen in 2 patients and both were male.