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In the present case the background cells were atypical and showed CD3, CD4, CD5, and CD25 phenotypes with a marked reduction of CD7 positivity, as observed in ATLL (1) and were negative for CD10 and PD1 enabling a differential diagnosis with angioimmunoblastic lymphoma, a disease that may also present HRS-like cells.
Patients with Hodgkin-like and pleomorphic small cell types have better survival compared with ALCL and angioimmunoblastic lymphoma type.
The hypermetabolic lymph nodes detected in PET-CT suggested T cell angioimmunoblastic lymphoma but it was ruled out with the histopathology of bone marrow and axillary lymph node.