angiogenic growth factors

angiogenic growth factors

Promoters of the production of new small blood vessels. They include VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF); acidic and basic fibroblast growth factor; transforming growth factor alpha and beta; tumour necrosis growth factor-alpha; platelet-derived growth factor; angiogenin; and interleukin-8.
References in periodicals archive ?
There have been efforts to treat ischemia by creating new blood vessels and delivering angiogenic growth factors like vascular endothelial growth factor (VEGF) to ischemic sites.
PGs have a tendency to develop within vascular lesions, suggesting an angiogenic stimuli of development, and increased expression of angiogenic growth factors (vascular endothelial growth factor and mitogen-activated protein kinase pathways) have been found in PGs.
In recent times, both type 1 and type II diabetes have been shown to influence angiogenic growth factors and inhibitors in skeletal muscle (6).
The surface features an increased amount of nano-scaled textures that result in the up-regulation of a greater amount of osteogenic and angiogenic growth factors critical for bone growth and fusion as compared to PEEK (polyether ether ketone) and the company's current surface.
HIF1A is associated with overexpression of other angiogenic growth factors such as formation of unstable/leaky vasculature (Hadjipanayi and Schilling, 2013).
3) This is consistent with expression of hypoxia-inducible angiogenic growth factors such as vascular endothelial growth factor in sporadic paragangliomas (4) and with the increased incidence of paragangliomas in patients with chronic hypoxia, such as those living at high altitudes.
Angiogenic growth factors in the diagnosis and prediction of pre-eclampsia.
There are four steps involved in the growth of blood vessels within tumors: i) the release of angiogenic growth factors by cancerous cells, ii) the disintegration of the basement membrane of a pre-existing capillary through the action of MMPs, iii) the proliferation and migration of endothelial cells to form sprouts, and iv) the formation of a capillary tube through the eventual contact of sprouts (Li et al.
Currently, Cleveland Clinic doctors are participating in a trial in which angiogenic growth factors (natural proteins that stimulate cell growth and differentiation) are injected directly into leg muscles of PAD patients to see if new blood vessels will grow and reconnect with the larger vessels, resulting in improved blood flow in the leg.
Using a multidisciplinary approach, the authors of these 20 articles cover the latest in studies of CAS and include such topics as epidemiology, pathophysiology, imaging, antithrombotic therapy, stroke prevention, management of hypertension, diet, angiogenesis and angiogenic growth factors as future therapies for cerebrovascular disease, risks and benefits, surgical controversies, symptomatic occlusion, stenting, and endovascular therapies.
In addition, Corautus is licensing certain intellectual property from CSEMC, including its pending patent applications covering the use of angiogenic growth factors for the treatment of peripheral neuropathy.