angiogenic growth factors

angiogenic growth factors

Promoters of the production of new small blood vessels. They include VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF); acidic and basic fibroblast growth factor; transforming growth factor alpha and beta; tumour necrosis growth factor-alpha; platelet-derived growth factor; angiogenin; and interleukin-8.
References in periodicals archive ?
Understanding of angiogenesis in the pulp-dentine complex is still in its infancy, and most studies have considered the effects of angiogenic growth factors, but these responses depend on binding of growth factors to tyrosine receptors.
These include trauma, surgery, nasal packing, hormones, viral oncogenes, arteriovenous malformations and angiogenic growth factors (1).
The maternal decidua, in which the decidual defect is a major contributing factor to PP formation, have a role in the expression of angiogenic growth factors (VEGF and PlGF).
Angiogenic growth factors are endogenous molecules that regulate growth and development of the microvessels [7].
There have been efforts to treat ischemia by creating new blood vessels and delivering angiogenic growth factors like vascular endothelial growth factor (VEGF) to ischemic sites.
PGs have a tendency to develop within vascular lesions, suggesting an angiogenic stimuli of development, and increased expression of angiogenic growth factors (vascular endothelial growth factor and mitogen-activated protein kinase pathways) have been found in PGs.
Decidual vascularization and the expression of angiogenic growth factors and proteases in first trimester spontaneous abortions.
Angiogenic growth factors such as VEGF and bFGF can also stimulate the hard tissue-forming capacity of mesenchymal stem cells [45-48].
The participation of CD133+ GB stem cells in tumor blood vessel formation has also been confirmed in studies where these cells have been found to secrete markedly elevated levels of angiogenic growth factors such as VEGF, basic fibroblast growth factor, (bFGF), platelet derived growth factor (PDGF), and epidermal growth factor (EGF) [22, 30].
As a positive control, the HUVECs in the culture plate were treated with angiogenic growth factors (10 ng/mL vascular endothelial growth factor (VEGF; R&D Systems, MN, USA) and 1 ng/mL basic fibroblast growth factor (bFGF; Sigma)).