angiogenic growth factor


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angiogenic growth factor

Any of a group of polypeptides that stimulate the formation of new blood vessels. They include agents like vascular endothelial growth factor (VEGF) and blood vessel fibroblastic growth factor (bFGF). These factors are active in healing wounds, chronic inflammatory conditions, retrolental fibroplasia, and malignant tumors, which require new blood vessels for continued growth.
See also: factor
References in periodicals archive ?
This results in revascularization and microcirculatory improvement, including an increase in arterial vessel diameter (arteriogenesis), the production of angiogenic growth factors, enhanced new blood vessel formation (angiogenesis), and the subsequent regeneration of tissue such as skin, musculoskeletal and vascular structures.
Taken together, the results of the Angiogenesis Study demonstrate that MiMedx dHACM allografts: 1) contain angiogenic growth factors retaining biologic activity; 2) promote amplification of angiogenic cues by inducing endothelial proliferation and migration and by upregulating production of endogenous growth factors by endothelial cells; and 3) support the formation of blood vessels in vivo.
Previous approaches have included the use of angiogenic growth factors and the fabrication of artificial blood vessels.
This results in revascularization and microcirculatory improvement, including the production of angiogenic growth factors, enhanced new blood vessel formation (angiogenesis), and the subsequent regeneration of tissue such as skin, musculoskeletal and vascular structures.