angiogenic factor

angiogenic factor

Any of a group of substances present in the circulation (most of which are polypeptides—e.g., angiogenin, fibroblast growth factor, transforming growth factors and some lipids) which play a role in blood vessel formation. Angiogenic factors are increased after myocardial ischaemia.

angiogenic factor

Any of a group of substances present in the circulation–most of which are polypeptides–eg, angiogenin, fibroblast growth factor, transforming growth factors, some lipids which help form blood vessels; AFs ↑ after myocardial ischemia
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Taken together, these findings suggest that gonadotropins induce the production of an angiogenic factor that stimulates the proliferation of capillaries from the vascular wreath present in the theca layer and promotes follicular development.
Vascular Endothelial Growth Factor A (VEGF-A) is the most specific and prominent angiogenic factor among all VEGF family members.
RESULTS: A 48-month follow-up revealed that the combination treatment with VK and ACE-I markedly inhibited the cumulative recurrence of HCC in association with suppression of the serum level of the vascular endothelial growth factor (VEGF); a central angiogenic factor.
Among these marker proteins, placental growth factor (PLGF), a member of the vascular endothelial cell growth factor (VEGF) family, is produced chiefly by the placenta and is a potent angiogenic factor.
At that time he thought there was something called tumor angiogenic factor that was being released, and he hypothesized that if we could stop this process we could ultimately stabilize the disease.
Conversely, the key angiogenic factor, vascular endothelial growth factor (VEGF-A, termed from hereon VEGF), as well as other members of its family such as VEGF-C and VEGF-D, and their receptors, are expressed in neuronal cells and participate in processes such as neurogenesis, neuronal migration, axon guidance, dendritogenesis and dendrite maintenance4-10.
Shh can increase angiogenic factor ANGPT1, and its upregulation possibly enhanced ANGPT1-mediating reciprocal interactions with TIE-2/Akt pathway between the endothelium and surrounding matrix and mesenchyme, and subsequent blood vessel maturation and stability (Fiedler et al.
It also acts as an angiogenic factor inducing blood vessels, promotes tumoral invasion, activates cancer stem cells, and in some tumors, induces metastases.
Previous data from this research group showed that increased circulating serum levels of the angiogenic factor soluble fms-like tyrosine kinase (sFlt-1) were predictive of subsequent preeclampsia (N.
As for all screening tests the positive predictive value of angiogenic factor screening depends on the population tested.