Using fluorescence in situ hybridization probes to detect rearrangements of TGFBR3 and MGEA5 in 31 pure MIFSs, 8 hybrid tumors, 2 pleomorphic hyalinizing angiectatic
tumors (PHATs), and 2 HFLTs, they observed that TGFBR3 and MGEA5 rearrangements were largely limited to hybrid HFLT-MIFS (6 of 8 cases), PHAT, and HFLT, and only rarely detected in pure MIFS.
PTX, a nonselective phosphodiesterase inhibitor, inhibits the conversion of cAMP to AMP, increases cAMP levels, improves cell function and hemorheology, and possesses an angiectatic
nasal polyps that clinically simulate a malignant process arch pathol lab med 124 (3): 406-410.
dermal fibroma), (6) pleomorphic fibroma, (7) cellular digital fibroma, (8) superficial acral fibromyxoma, (9) pleomorphic hyalinizing angiectatic tumor of soft parts, (10) and malignant lesions such as dermatofibrosarcoma protuberans (DFSP).
Pleomorphic hyalinizing angiectatic tumor of soft parts: immunohistochemical case study shows cellular composition by CD34+ fibroblasts and factor XIIIa+ dendrophages.
fibroblastic tumor Neural neoplasms Neurofibroma Nerve sheath myxoma Perineurioma Lipogenic neoplasms Spindle cell lipoma/pleomorphic lipomas Neoplasms of unknown lineage Pleomorphic hyalinizing angiectatic tumor of soft parts Epithelioid sarcoma Table 2.
Three cases of pleomorphic hyalinizing angiectatic tumor (PHAT) and 3 other cases of non-MIFS were tested, all of which were negative for t(1; 10).
20,21) Pleomorphic hyalinizing angiectatic tumor also occurs at similar sites and age as HFLT, with a common biologic behavior.