aneuploidy theory

aneuploidy theory

A paradigm for explaining carcinogenesis which holds that nearly all cancer cells are aneuploid because they began that way; according to Duesberg, the aneuploidy theory’s main proponent, no gene mutations are required for cancer to develop.
References in periodicals archive ?
The aneuploidy theory of cancer was introduced by David von Hansemann in 1890 and formally stated by Theodor Boveri in 1914.
Some American researchers, eager to dismiss the aneuploidy theory, ask, what is the mechanism; meaning, how does aneuploidy cause cancer?
Boveri pointed out that his aneuploidy theory explains the increasing risk of cancer with age because in aging cells, division is more frequently disturbed.
The aneuploidy theory of cancer is as valid today as it was in 1914.