Also found in: Dictionary, Encyclopedia, Wikipedia.
Related to androstenedione: DHEA, androstenediol


an androgen, C19H30O2, less potent than testosterone, secreted by the testis, ovary, and adrenal cortex.


Androstanedione with a double bond between C-4 and C-5; an androgenic steroid of weaker biologic potency than testosterone; secreted by the testis, ovary, and adrenal cortex.


/an·dro·stene·di·one/ (-di-ōn) an androgenic steroid produced by the testis, adrenal cortex, and ovary; converted metabolically to testosterone and other androgens.


An unsaturated androgenic steroid, C19H26O2, that is secreted by the testis, ovary, and adrenal cortex and is a precursor of both androgens and estrogens. Until 2005, when its nonprescription sale and use became illegal in the United States, synthetic androstenedione was used as a dietary supplement to enhance athletic performance.


An androgenic steroid less potent than testosterone, which is produced by the adrenal cortex, ovary and testis and converted to estrone in fat and the liver; in men, overproduction of androstendione may cause feminisation.
Increased in
Cushing syndrome; ovarian, testicular or adrenocortical tumours; adrenal hyperplasia; polycystic ovary disease.

Decreased in
Hypogonadism, Addison’s disease.
Ref range
Women (premenopausal)—0.5–3 ng/mL; women (postmenopausal)—0.3-8 ng/mL; men—0.9–1.7 ng/mL.


An androgenic steroid, less potent than testosterone, which is produced by the adrenal cortex and gonads, and converted to estrone in fat and the liver; in ♂, overproduction of androstendione may cause feminization; androstenedione is ↑ in Cushing syndrome, ovarian, testicular, or adrenocortical tumors, adrenal hyperplasia, polycystic ovary disease; it is ↓ in hypogonadism, Addison's disease


An androgenic steroid of weaker biologic potency than testosterone; secreted by the testis, ovary, and the cortex of the suprarenal gland.
See also: performance enhancing drug


Also called "andro," this hormone occurs naturally during the making of testosterone and estrogen.
Mentioned in: Anabolic Steroid Use

androstenedione (anˑ·drō·steˈ·n·dīˈ·ōn),

n a biochemical precursor to both estrogen and testosterone. Used as a dietary supplement because it is believed to boost testosterone levels and claimed to increase athletic performance and muscle mass. It increases estrogen levels more than testosterone, may interfere with hormone levels, and may heighten the risk of hormone-sensitive cancers or cancers of the liver.


an androgenic steroid produced by the testis, adrenal cortex and ovary. Immunization against it gives excellent results in promoting fertility in ewes by increasing the twinning rate.

Patient discussion about androstenedione

Q. What is the difference between ADD and ADHD? My Son has been diagnosed with ADD. Is this the same as ADHD?

A. Here is the general description:
ADHD: Think of these types of children as the energizer bunnies in constant motion. They tend to move about excessively, fidgeting and squirming, and always into things. Remaining seated when expected to is often an impossible task.
ADD: Children with predominately inattentive behaviors, more commonly referred to as ADD, may act very differently. These are the “daydreamers.” They may appear spacey, forgetful, and distracted. They move from one activity to the next, never quite able to complete a task. Often times they begin a task without waiting for the directions and end up frustrated and uncertain. They may seem rather messy, careless and disorganized.

Q. Is there any connection between ADD and Autism? I refer to ADD, not ADHD

A. there is a theory that ADD and learning disabilities are a "continuum" up to Asperger syndrome and autism. due to similarities in brain function and symptoms. mind you- it's a theory.

Q. What is the difference between ADD and ADHD? I know that H stands for hyperactivity, but what does it mean by symptoms? does It have the same treatment?

A. They differ by ADHD kids tend to move around all the time (not like ADD who can sit but not listen), and they are more then careless. They tend to injure themselves over childhood. <br>I saw a nice video that explains about those disorders! <br><object width='425' height='355' id='FiveminPlayer'><param name='allowfullscreen' value='true'/><param name='movie' value=''/><embed src='' type='application/x-shockwave-flash' width='425' height='355' allowfullscreen='true'></embed></object>

More discussions about androstenedione
References in periodicals archive ?
In addition to its role in the biosynthesis of 3[beta]-Adiol from 5a-DHT, this nicotinamide adenine dinucleotide (NAD (+))-dependent enzyme catalyzes the conversion of pregnenolone, 17[alpha]-hydroxypregnenolone, DHEA, and androstenediol into their respective ketosteroids: progesterone, 17a-hydroxyprogesterone, androstenedione, and testosterone (Figure 1).
Androstenedione, testosterone, and 17OHP were monitored in a single analytic run using a mobile phase variably consisting of 50%-100% methanol and employing primary transitions of m/z 287[right arrow]97, 289[right arrow]97, and 331[right arrow]97, respectively.
The low testosterone and androstenediol glucuronide, high androstenedione and estrone levels are consistent with testosterone synthetic defect due to 17-[beta]-HSD3 deficiency.
Dihydrotestosterone and androstenedione appeared to inhibit macrophage migration and attraction to the implant compared to testosterone and control.
The PCOS group received daily injecttions of androstenedione at a concentration of 6 mg/100 g body weight dissolved in 200 [micro]l corn oil for 21 days.
The principal androgens are testosterone and androstenedione.
Plasma ACTH was low and DHEA, androstenedione and testosterone were all elevated.
2) Studies on healthy young men found no improvement in skeletal muscle adaptation to resistance training with androstenedione supplementation for 8 to 12 weeks.
Jones escaped without punishment when it was revealed he had tested positive for the anabolic steroid androstenedione after a fight against fellow American Richard Hall in 2000.
These include androstenedione, chamomile, DHEA, goldenseal, kava-kava, nettle, passionflower, sage, St.
The problem is, androstenedione promotes hair loss.