androstenediol


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androstenediol

 [an″dro-stēn´de-ol]
a crystalline androgenic steroid, C19H30O2.

an·dro·stene·di·ol

(an'drō-stēn'dī-ol),
A steroid metabolite differing from androstanediol by possessing a double bond between C-5 and C-6.

an·dro·stene·di·ol

(an'drō-stēn'dī-ol)
A steroid metabolite differing from androstanediol by possessing a double bond between C-5 and C-6.
References in periodicals archive ?
Adrenal-derived DHEA-S and DHEA is converted by 3[beta]-hydroxysteroid dehydrogenase (3[beta]-HSD) into androstenedione and testosterone --the latter being the downstream metabolite of androstenediol produced from DHEA via I7[beta]-HSD Type V, which is in close proximity to 3[beta]-HSD In the prostate epithelium.
Assay Specificity (cross-reactivity of antiserum) Progesterone < 0.001 % to cortisol, corticosterone, androstenediol, pregnenolone, estradiol, testosterone Estradiol < 0.01 % to DHEA, progesterone, cortisol, androsterone, testosterone, androstenedione, corticosterone, cortisone Assay Sensitivity coefficient of variation (%) Intra-assay Inter-assay Progesterone 0.12 ng/ml < 8.0 < 13.1 Estradiol 6.5 pg/ml < 9.4 < 19.2 Table 2.
17-[beta]-HSD4 inactivates both estradiol into estrone and A5 androstenediol into dehydroepiandrosterone (DHEA).
Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage.
The biosynthetic pathway via DHEA leads to the production of androstenedione (DIONE) and androstenediol (DIOL).
Once synthesized from cholesterol, pregnenolone may be further converted into DHRA, which is the precursor of androstenediol. Androstenediol in turn is converted to testosterone and estradiol.
A maioria dos estudos analisados apontou maior risco de contaminacao em suplementos para aumento de forca e massa muscular, como os pre-hormonais (DHEA, androstenediol, androstenediona, norandrostenediol e norandrostenediona) (Van Der Merwe e Grobbelaar, 2005; Geyer e colaboradores, 2004; Catlin e colaboradores, 2000).
The ability of 667 COUMATE to inhibit STS in tumour samples obtained from some patients and its effect on serum androstenediol and oestrogen concentrations was also measured during the trial.9,27
Additionally, androstenediol has been modeled as a chemical with a 3/5-hydroxy and a saturated A ring which can act as an estrogen [23].
We measured metabolites of 3 steroids, namely dehydroepiandrosterone (DHEA), androstenedione (AD4), and 11[beta]-hydroxyandrostenedione (11OHAD4), and calculated the sum of DHEA metabolites (DHEA, androstenediol, 16[alpha]-hydroxy-DHEA, 16[beta]-hydroxy-DHEA, 16-oxo-androstenediol, and androstenetriol), the sum of AD4 metabolites (androsterone and etiocholanolone) (8, 10), and the 11OHAD4 metabolite (11HA).
The effects of androstenediol and dehydroepiandrosterone on the course and cytokine profile of tuberculosis in BALB/c mice.
Third, Androstenediol is a steroid metabolite and act as main regulatory agent of gonadotropin secretion.