androstanediol

androstanediol

 [an″dro-stān´de-ol]
an androgen, C19H32O2, prepared by reducing androsterone.

an·dro·stane·di·ol

(an'drō-stān'dī-ol),
A steroid metabolite, of which 5β isomers are also known.

an·dro·stane·di·ol

(an'drō-stān'dī-ol)
5α-androstane-3β,17β-diol; a steroid metabolite, of which 5β isomers are also known.
References in periodicals archive ?
" Ogawa, 31, scored a split 12-round decision over Tevin Farmer for the IBF superfeatherweight title in Las Vegas in 2017 but the outcome was later ruled a No Contest after the Japanese tested positive for androstanediol, a banned steroid.
9, after the 30-year-old's pre-fight tests were positive for two forms of androstanediol.
There are two groups of families of neurosteroids: the inhibitory neurotransmitter receptor families of pregnane neurosteroids that include allopregnanolone and aIlotetrahydrodeoxycorticosterone, and the excitatory neurotransmitter receptor families of androstane neurosteroids, such as androstanediol and etiocholanone.
Abbreviations 3[alpha]-HSD: 3[alpha]-Hydroxysteroid dehydrogenase ALLO: Allopregnanolone DHT: Dihydrotestosterone DIOL: Androstanediol [IC.sub.50]: Half maximum inhibitory concentrations RDH2: Retinol dehydrogenase 2 5[alpha]-Red1: 5[alpha]-Reductase 1 TEB: Tebuconazole T: Testosterone TRI: Triadimefon VCZ: Vinclozolin.
concluded after 8 years of follow-up that testosterone and other androgens (dihydrotestosterone or androstanediol) were not associated with prostate cancer risk.
Odds ratios (95% confidence intervals) for mortality for increasing quartiles of endogenous testosterone compared with the lowest quartile were 0.75 (0.55 to 1.00), 0.62 (0.45 to 0.84), and 0.59 (0.42 to 0.85), respectively (P<0.001 for trend after adjustment for age, date of visit, body mass index, systolic blood pressure, blood cholesterol, cigarette smoking, diabetes mellitus, alcohol intake, physical activity, social class, education, dehydroepiandrosterone sulfate, androstanediol glucuronide, and sex hormone binding globulin).
Three of the metabolites comigrated with androstenedione, dihydrotestosterone, and androstanediol. We grouped these metabolites together as oxido-reduction metabolites.
The testosterone metabolites androsterone and etiocholanolone can be measured in 24-hour urine, while the best androgen metabolites in the serum to assess are dihydrotestosterone and androstanediol glucuronide, which concentration is on the average double that of testosterone.
Wilson, "The induction of prostatic hypertrophy in the dog with androstanediol," Journal of Clinical Investigation, vol.
Termed "testosterone metabolites," this blood serum test also measures androstenedione (spelled almost but not quite exactly the same way as "androstanediol"), another androgen metabolite, and 3 [alpha] -Adiol (full name: 5 [alpha] -androstane-3 [alpha], 17 [beta] -diol.
A review by the Biology of Reproduction Journal states: We believe that a higher incidence of low-differentiated tumors in the finasteride-treated arm observed in the PCPT is caused by altering the normal differentiation of prostatic epithelium in the environment lacking the natural ER[beta] ligand--3[beta] androstanediol. (14)