androstane


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androstane

 [an´dro-stān]
the hydrocarbon nucleus, C19H32, from which androgens are derived.

an·dro·stane

(an'drō-stān),
The parent hydrocarbon of the androgenic steroids. For structure, see steroids.

androstane

/an·dro·stane/ (an´dro-stān) the hydrocarbon nucleus, C19H32, from which androgens are derived.

an·dro·stane

(an'drō-stān)
The parent hydrocarbon of the androgenic steroids.

androstane

the hydrocarbon nucleus, C19H32, from which androgens are derived.
References in periodicals archive ?
Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters.
Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR).
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.
Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha.
The genes modified by DEHP in PPAR[alpha]-null mice included those involved in xenobiotic metabolism, including targets of constitutive androstane receptor (CAR) or pregnane X receptor (PXR), and cholesterol biosynthesis which is regulated by other transcription factors, including retinoid X receptor (RXR) (Ren et al.
In addition to the AHR, Insig1 is regulated by multiple nuclear receptors including PPARa (15 AHR REs), CAR (constitutive androstane receptor; 2 AHR REs), and PXR (pregnane X receptor).
In comparison, some non-dioxin-like PCBs such as PCB-153 do not activate AhR but may be constitutive androstane receptor agonists (Dean et al.
Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).
Although our results clearly demonstrate DEHP-mcdiated metabolic interference via PPAR[alpha], other metabolic pathways--such, as those driven by CAR (constitutive androstane receptor) and Rev-Erb[alpha] (nuclear receptor subfamily 1, group D, member 1)--could also be involved (Eveillard et al.
The cytochromes chosen were biomarkers for activation of aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR), and PXR.
Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.