androgen


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androgen

 [an´dro-jen]
any steroid hormone that promotes male secondary sex characters. The two main androgens are androsterone and testosterone. Called also androgenic hormone. adj., adj androgen´ic. 

The androgenic hormones are internal endocrine secretions circulating in the bloodstream and manufactured mainly by the testes under stimulation from the pituitary gland. To a lesser extent, androgens are produced by the adrenal glands in both sexes, as well as by the ovaries in women. Thus women normally have a small percentage of male hormones, in the same way that men's bodies contain some female sex hormones, the estrogens. Male secondary sex characters include growth of the beard and deepening of the voice at puberty. Androgens also stimulate the growth of muscle and bones throughout the body and thus account in part for the greater strength and size of men as compared to women.
androgen insensitivity syndrome complete androgen resistance.

an·dro·gen

(an'drō-jen),
Generic term for an agent, usually a hormone (for example, androsterone, testosterone), which stimulates activity of the accessory male sex organs, encourages development of male sex characteristics, or prevents changes in the latter due to castration; natural androgens are steroids, derivatives of androstane.
Synonym(s): testoid (2)

androgen

(ăn′drə-jən)
n.
A steroid hormone, such as testosterone or androsterone, that controls the development and maintenance of masculine characteristics. Also called androgenic hormone.

an′dro·gen′ic (-jĕn′ĭk) adj.

an·dro·gen

(an'drŏ-jen)
Generic term for an agent, usually a hormone (e.g., androsterone, testosterone), which stimulates activity of the accessory male sex organs, promotes development of male sex characteristics, or prevents changes in the latter that follow castration; natural androgens are steroids, derivatives of androstane.

androgen

one of several types of male hormone that stimulate the development and maintenance of the male's SECONDARY SEXUAL CHARACTERISTICS. Naturally occurring androgens (e.g. TESTOSTERONE) are STEROIDS which are produced mainly in the testis (see INTERSTITIAL CELLS), but also to a small extent in the OVARY and ADRENAL CORTEX.

Androgen

A natural or artificial steroid that acts as a male sex hormone. Androgens are responsible for the development of male sex organs and secondary sexual characteristics. Testosterone and androsterone are androgens.

an·dro·gen

(an'drŏ-jen)
Generic term for an agent, usually a hormone (e.g., androsterone, testosterone), which stimulates activity of the accessory male sex organs, encourages development of male sex characteristics, or prevents changes in the latter due to castration.
References in periodicals archive ?
The intensity of AR staining on IHC is determined by assigning certain scores ranging from 0-3, where 0 means no staining, 1 means weak equivocal staining, 2 means unequivocal moderate staining and 3 represents strong staining.23 In the current study the Androgen Receptor was detected in 59 cases (98.33%) and was not detected in only 1 case (1.67%) so its score was graded as 0.
Treatment includes androgen receptor blocker, lowering androgen production by adrenals and ovaries.9
[3,4,5,6,7,8] The Androgen receptor positivity percentage of this set of triple negative patients was compared with the data in the literature.
Although AR or high levels of circulating plasma androgens have been documented in females in a wide array of taxa (Iela et al., 1986; Yalcinkaya et al., 1993; Yoshimura et al., 1993), the molecular mechanism of androgen action and the role of AR in the female birds reproductive tract have not yet been demonstrated.
Hyperandrogenism refers to the condition in which excessive androgens are found circulating in the female body.
To examine if KH-204 can increase androgen synthesis in the androgen-deprived rat, we analyzed influences of KH-204 on the contents of serum testosterone and 3[beta]-HSD activities.
Blocking extracellular signal regulated kinase (ERK) pathway by inhibitor PD98059 has been shown to induce androgen excess [23, 24].
In prostate cancer, the androgen receptor (lock) is activated by the androgen (key) resulting in a signal that causes prostate cancer proliferation.
Editor's Note: "Based on the results of our study, an increased risk of Alzheimer's disease is a potential adverse effect of androgen deprivation therapy, but further research is needed before considering changes to clinical practice," Dr.
Inflammatory changes of the lacrimal gland in patients with androgen deficiencies in autoimmune disease such as Sjogren's syndrome results in aqueous deficient dry eye.
Today, there is a global concern regarding endocrine disruption effects, particularly those mediated by the androgen receptor (AR).
Androgens are a group of hormones that play a role in male traits and reproductive activity.