However, quantification of anaplerotic reactions and glyoxylate shunt on the growth of C.
Anaplerotic reactions are responsible to maintain TCA pools which are utilized for lysine biosynthesis.
Gayen and Venkatesh included only PEP carboxylase as only anaplerotic reaction omitting glucogeneosis from their network.
glutamicum to study the fluxes of the anaplerotic reactions while the organism grows on mixed substrates of glucose and lactate.
2007) Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis, Microbial Cell Factories 6: 11.
2001) Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo, Metabolic Engineering 3: 344-361.