anaplerotic

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an·a·ple·rot·ic

(an'ă-pler-ŏ'tik),

Referring to reactions or pathways that contribute to anaplerosis.

anaplerotic

adjective Referring to anaplerosis (obsolete).

Mentioned in ?

anaplerotic metabolic pathway

References in periodicals archive ?

Human ESC also make extensive use of glutaminolysis [10], which metabolic modelling suggests is likely used for ATP and synthesis of antioxidants (glutathione and NADPH), and anaplerotic pathways [93].

Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP

Vestermarket al., "Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling," Journal of Biological Chemistry, vol.

Coordinated actions of FXR and LXR in metabolism: from pathogenesis to pharmacological targets for type 2 diabetes

However, quantification of anaplerotic reactions and glyoxylate shunt on the growth of C.

Anaplerotic reactions are responsible to maintain TCA pools which are utilized for lysine biosynthesis.

Gayen and Venkatesh included only PEP carboxylase as only anaplerotic reaction omitting glucogeneosis from their network.

glutamicum to study the fluxes of the anaplerotic reactions while the organism grows on mixed substrates of glucose and lactate.

In silico quantification of optimal lysine synthesis during growth of corynebacterium glutamicum on mixed substrates (Glucose and Lactate)

Increased lactate concentration is an anaplerotic effect of alkalaemia (33,34), operating as a feedback loop which buffers pH swings (35,36).

Acid-base and bio-energetics during balanced versus unbalanced normovolaemic haemodilution

Non-autotrophic uses of dark-fixed carbon include involvement as a pH stat mechanism for reducing cytoplasmic ionic disequilibrium (Raven, 1986) or in anaplerotic reactions related to nitrogen assimilation (Turpin et al., 1991).

CAM photosynthesis in submerged aquatic plants

A clear difference, however, was seen at the level of the cataplerotic enzyme ATP-citrate lyase (ACLY) and anaplerotic enzyme pyruvate carboxylase (PC) both more abundant in rat beta cells (Figure 2(c)); again this is remarkable as the anaplerotic flux of glucose-carbon through PC is considered an important regulator of glucose-stimulated insulin secretion based on rodent studies.

In rodents, this anaplerotic flux was quantitatively important and considered crucial for GSIS [29].

Stephanopoulos, "Effect of anaplerotic fluxes and amino acid availability on hepatic lipoapoptosis," Journal of Biological Chemistry, vol.

Nonalcoholic fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective

This is achieved either by being an anaplerotic source in a complete TCA cycle, or as a direct bioenergetic substrate in a truncated cycle [20].

Metabolic fate of the increased yeast amino acid uptake subsequent to catabolite derepression