anaplastic meningioma

anaplastic meningioma

An aggressive form of meningioma, which is defined histologically as having > 20 mitoses/10 high-power fields and/or marked cytologic atypia.
References in periodicals archive ?
There were not any features suggestive of atypical or anaplastic meningioma such as nuclear pleomorphism, increased mitosis, atypical mitosis or necrosis.
Atypical meningioma can have malignant transformation to anaplastic meningioma, so aggressive treatment and follow-up are essential to manage this particular tumor.
81%) were proved to have malignant transformation to anaplastic meningioma from atypical meningioma during the following operations to their recurrent disease.
Ramzan, "Intraparenchymal anaplastic meningioma in a child: a rare entity," Asian Journal ofNeurosurgery, vol.
Out of 10 malignant glial tumours 5 cases (50%) were reported as glioblastoma, 4 cases (40%) were reported as high grade astrocytoma and in one case suspicion of anaplastic meningioma was offered which was confirmed on paraffin section.
Ki-67 proliferative index predicts clinical outcome in patients with atypical or anaplastic meningioma.
Immunohistochemicalstudy of Ki-67 (MIB-1), p53 protein, p21WAF1, and p27KIP1 expression in benign, atypical, and anaplastic meningiomas.
Twenty-seven cases of WHO grade I meningiomas would have increased in grade to atypical meningiomas (WHO grade II), and one atypical meningioma would have increased to anaplastic meningioma (WHO grade III).
Ki-67 proliferative index predicts clinical outcomes in patients with atypical or anaplastic meningioma.
One case diagnosed as glioblastoma multiforme as it showed strong reactivity for GFAP, vimentin and negative for EMA, which ruled out possibility of anaplastic meningioma.
1) The WHO 2007 definition of anaplastic meningioma includes "high mitotic index in excess of 20 per 10 high power fields or histological features of frank malignancy.
Amatya et al (57) studied 146 cases of meningiomas immunohistochemically and reported that the mean MIB-1 LI of benign, atypical, and anaplastic meningiomas was 1.