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3) Anaplastic carcinoma of the thyroid, which is rare, has a propensity to invade adjacent structures, and it often presents with vocal fold paralysis.
OXiGENE's Combretastatin A4 Prodrug (CA4P) will be studied in combination with the chemotherapy drugs doxorubicin/cisplatin and radiation in patients with newly diagnosed anaplastic carcinoma of the thyroid (ATC).
OXiGENE's lead compound, Combretastatin A4 Prodrug (CA4P), is being evaluated in three concurrent clinical trials, including a Phase II study in patients with advanced anaplastic carcinoma of the thyroid.
We have delivered on each planned milestone in 2002, including most notably the initiation of a Phase II trial in advanced anaplastic carcinoma of the thyroid," Driscoll said.