anaplastic astrocytoma


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an·a·plas·tic as·tro·cy·to·ma

intermediate grade astrocytoma characterized by increased cellularity, nuclear pleomorphism, and mitoses.

anaplastic astrocytoma

anaplastic astrocytoma

A high-grade tumour of astrocytes in the CNS, histologically characterised by increased mitotic activity and increased cellularity, which may make it difficult to differentiate from grade-II astrocytoma.

anaplastic astrocytoma

A relatively aggressive and invasive brain tumor derived from supporting cells in the brain. It typically is diagnosed in people aged 30-50, in whom it often causes symptoms such as headache and seizures. Anaplastic astrocytomas are known as grade III astrocytomas under the WHO grading system.
See also: astrocytoma
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Mr Newman, of Shilburn Road, Allendale, Northumberland, was diagnosed with an anaplastic astrocytoma tumour, which attaches itself to the brain, after he collapsed at work in August 2003.
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In 1999 Temodar was granted accelerated approval for the treatment of adult patients with anaplastic astrocytoma (another form of brain cancer) in relapse after chemotherapy with nitrosourea and procarbazine.
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