anaplastic astrocytoma


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an·a·plas·tic as·tro·cy·to·ma

intermediate grade astrocytoma characterized by increased cellularity, nuclear pleomorphism, and mitoses.

anaplastic astrocytoma

A high-grade tumour of astrocytes in the CNS, histologically characterised by increased mitotic activity and increased cellularity, which may make it difficult to differentiate from grade-II astrocytoma.

anaplastic astrocytoma

A relatively aggressive and invasive brain tumor derived from supporting cells in the brain. It typically is diagnosed in people aged 30-50, in whom it often causes symptoms such as headache and seizures. Anaplastic astrocytomas are known as grade III astrocytomas under the WHO grading system.
See also: astrocytoma
References in periodicals archive ?
Yoshimoto et al., "MiRNA-196 is upregulated in glioblastoma but not in anaplastic astrocytoma and has prognostic significance," Clinical Cancer Research: an Official Journal of the American Association for Cancer Research, vol.
Madden et al., "Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients," Oncology Reports, vol.
These markers may assist significantly in the evaluation of proliferative activity in anaplastic astrocytomas and even have prognostic value.
While antineoplaston therapy does not cure all patients, it has a much better record, even with difficult cancers (e.g., anaplastic astrocytoma and glioma), than conventional treatment; and it does not cause damaging side effects.
Tew said that the three-dimensional brain-mapping enabled his team to navigate a trajectory through the patient's brain, and to remove 90 percent of the malignant tumour, an anaplastic astrocytoma, without harming the healthy brain tissue-including the deep nerve-fibre tracts-that surrounded it.
My once-Grade III Anaplastic Astrocytoma with features of a Grade IV Glioblastoma Multiforme had morphed into a recurrent malignant glioma within 13 months of my initial diagnosis.
The biopsy also revealed the tumour was an anaplastic astrocytoma and there was no cure.
We hypothesized that any peptide peaks that progressively change with increasing malignancy (control [right arrow] grade II astrocytoma [right arrow] anaplastic astrocytoma [right arrow] GBM) are potential survival biomarkers for patients with GBM.
Mr Newman, of Shilburn Road, Allendale, Northumberland, was diagnosed with an anaplastic astrocytoma tumour, which attaches itself to the brain, after he collapsed at work in August 2003.
In Japan, it is estimated that about 2,500 people develop GBM annually, of whom about 2,200 people are diagnosed as anaplastic astrocytoma.
We report a case of nasal glioma in a 6-month-old boy in which the histomorphologic features resembled those of an anaplastic astrocytoma.
In 1999 Temodar was granted accelerated approval for the treatment of adult patients with anaplastic astrocytoma (another form of brain cancer) in relapse after chemotherapy with nitrosourea and procarbazine.