anaplasia


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Related to anaplasia: metaplasia

anaplasia

 [an″ah-pla´zhah]
loss of differentiation of cells and their orientation to each other, a characteristic of tumor cells; called also dedifferentiation and undifferentiation.

an·a·pla·si·a

(an'ă-plā'zē-ă),
Loss of structural differentiation, especially as seen in most, but not all, malignant neoplasms.
Synonym(s): dedifferentiation (2)
[G. ana, again, + plasis, a molding]

anaplasia

/ana·pla·sia/ (-pla´zhah) dedifferentiation; loss of differentiation of cells and of their orientation to one another and to their axial framework and blood vessels, a characteristic of tumor tissue.anaplas´tic

anaplasia

(ăn′ə-plā′zhə)
n.
Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.

anaplasia

[an′əplā′zhə]
Etymology: Gk, ana + plassein, to shape
a change in the structure and orientation of cells, characterized by a loss of differentiation and reversion to a more primitive form. Anaplasia is characteristic of malignancy. Compare aplasia. anaplastic, adj.

anaplasia

A state in which a malignant cell or tissue has undergone structural or functional dedifferentiation to the point where its lineage and/or tissue of origin cannot be determined with complete certainty. Anaplastic tumours usually have high mitotic activity and bizarre cellular morphology.

an·a·pla·si·a

(an'ă-plā'zē-ă)
Loss of structural differentiation, especially as seen in most, but not all, malignant neoplasms.
Synonym(s): dedifferentiation (2) .
[G. ana, again, + plasis, a molding]

anaplasia

Loss of the cellular microscopic features which distinguish one type from another. Anaplastic cells become smaller and simpler in structure and no longer combine to form recognizable tissues. Anaplasia is a common feature of cancer and, in general, the greater the anaplasia the more malignant and dangerous the tumour.

anaplasia

the reversion of cells to a more undifferentiated form.

an·a·pla·si·a

(an'ă-plā'zē-ă)
Loss of structural differentiation, especially as seen in most, but not all, malignant neoplasms.
Synonym(s): dedifferentiation (2) .
[G. ana, again, + plasis, a molding]

anaplasia (an´əplā´zhə),

n a regressive change in cells toward a more primitive or embryonic cell type. It is a prominent characteristic of malignancy in tumors.

anaplasia

loss of differentiation of cells, an irreversible alteration in adult cells toward more primitive (embryonic) cell types; a characteristic of tumor cells.
References in periodicals archive ?
6-4 20 Grade Name Pathological Features Subtypes I Benign Well circumscribed -- II Atypical Three of five Choroids or clear cell Loss of lobularity Small cells Prominent nucleoli Increased cellularity Necrosis III Anaplastic Anaplasia and Rhabdoid or papillary Brain invasion TABLE 2.
El mesotelioma epitelioide, compuesto solamente por celulas mesoteliales epitelioides con variante grado de anaplasia y un alto numero de figuras mitoticas por campo, con un aumento total de 40x (Fig.
Rhabdomyosarcoma expression of both CK-MB and cTnT can be explained by tumor anaplasia and concurrent expression of fetal phenotypes.
Anaplasia Loss of structural differentiation, especially seen in most, but not all, malignant cells.
The cells may show varying degree of anaplasia and mild-to-moderate nuclear atypia (Figure B).
The TILs are the hallmark of medullary carcinoma (MC) of breast, which, despite cytologic anaplasia, has a better prognosis than IDC-NOS.
Qualman S, Lynch J, Bridge J, Prevalence and clinical impact of anaplasia in childhood rhabdomy-osarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
All tumors were identified and categorized into blastemal, epithelial, stromal, mixed type, and anaplasia by pathologist after excision, according to National Wilms' Tumor Study (NWTS).
The benign nature of this lesion was suggested by the lack of any mitotic activity, anaplasia, or dysplasia.
Differentiation of low grade astrocytoma and normal cerebral tissue on cytology is difficult sometimes because the astrocytes display minimal to no anaplasia and are loosely dispersed in a delicate fibrillary background.
La ubicacion en tejidos profundos, hace que la neoplasia tenga un comportamiento mas agresivo; independiente de la presencia o no de las caracteristicas de malignidad tales como: mitosis, anaplasia y desdiferenciacion.