Although CBG does bind to the CB2 receptor, it has a low affinity toward both receptors and actually activates the endocannabinoid system by means of inhibiting
anandamide uptake.
Anandamide binds to type 1 cannabinoid receptors (CB1), which are also activated by THC, the main psychoactive cannabinoid in marijuana.
Cannabidiol enhances
anandamide signaling and alleviates psychotic symptoms of schizophrenia.
In this study, the effect of
anandamide on brain oxidative stress and the development of seizures in rats subjected to PTZ-kindling was investigated.
endocannabinoids,
anandamide (AEA) and 2-arachidonoylglycerol (2-AG).
Its best-documented effect is its ability to increase levels of
anandamide, a neurotransmitter that counteracts stress.
The vegan protein is also a natural source of
anandamide, phenethylamine, arginine & 300 other biological compounds found in nature, delivering a fully complete protein powder, which may additionally help to support active digestion, healthy skin, and muscle repair.
By these modulations, ECs,
anandamide, and 2-arachidonylglycerol increase in systemic circulation, and this effect has been shown to relieve pain in animal models.
Other cannabinoids interact with it as well, such as
anandamide - a compound produced naturally within our bodies.
The most important Hv1 activating factors are membrane depolarization, extracellular alkalization and
anandamide. Zinc (Zn) is the most potent inhibitory factor for Hv1 channel activity (11, 15).
Acetaminophen (Tylenol and others) is a fairly weak painkiller on its own, but it reduces some pain chemicals and enhances the effect of
anandamide, a cannabis-related mood-enhancing chemical made by our own bodies.
Blood levels of the endocannabinoid
anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa.
