analytical specificity

an·a·lyt·i·cal spec·i·fic·i·ty

freedom from interference by any element or compound other than the analyte.
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To assess analytical specificity by real-time PCR, DNA from the same samples used in conventional PCR was submitted to reaction amplification.
Analytical specificity is the likelihood that the assay will be negative when no variant is present (1--false-positive rate).
A total of 3692 variants, 61 pathogenic and 3631 benign variants, were identified by the smMIP approach, all previously seen by Sanger sequencing, resulting in a 100% analytical sensitivity and 100% analytical specificity.
isolates from the ESR culture collection The following known organisms were selected for inclusion in an analytical specificity panel, including six Y.
As the use of prophylactic HPV vaccines becomes more widespread, surveillance for population-levels of effectiveness is becoming an increasingly important activity, which requires the use of standardized HPV genotyping tests with analytical performance different from tests with clinically validated cutoffs; for example, tests with higher analytical sensitivity and absolute analytical specificity (10).
Validation of the product, with 250 priorly characterised samples, demonstrated 100% identification of 3,025 known variants and an analytical specificity of 99.
The analytical specificity of the COBAS TaqMan MTB test was further evaluated by using M.
To determine the analytical specificity of the assay, we tested 36 clinical strains of A.
More important, CLIA regulations require that before a laboratory introduces a new method or test that does not use a commercially available test kit, it must establish and document the performance specifications for accuracy, precision, analytical sensitivity, analytical specificity, and quality of results for patient care: all essential parameters of quality and performance.
Convenient and ready to use, this standardized, serially diluted panel will help users establish or verify performance specifications for the linearity, accuracy, precision, reportable range, analytical sensitivity, and analytical specificity of their BK virus assays.
How could one maximize the analytical specificity and sensitivity for the detection of rare mutant DNA molecules released from tumors?
An analytical specificity study on a panel of 41 bacteria, viruses, and fungi that can be found in the female anogenital tract revealed no cross-reactivity with any of the or-ganisms tested, including all relevant low-risk HPV genotypes (9).
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