Other measures were manually calculated like linearity, recovery, accuracy, precision, limitof detection and quantification, analytical specificity
accuracy, precision, analytical sensitivity, analytical specificity
including interfering substances, reportable range of test results, reference intervals, and any other performance characteristic required for test performance) for use in their patient population]; and
In addition, microscopy has limited analytical specificity
because AFB detected by microscopy may represent MTB or non-TB mycobacteria (NTM).
Natera says that Vistara has a combined analytical sensitivity of >99% and a combined analytical specificity
of >99% in validation studies.
Determination of the Analytical Specificity
of the Developed Assays.
To assess analytical specificity
by real-time PCR, DNA from the same samples used in conventional PCR was submitted to reaction amplification.
is the likelihood that the assay will be negative when no variant is present (1--false-positive rate).
Evaluation of Analytical Specificity
of Thermostabilized PCR.
Furthermore, this assay demonstrated high analytical specificity
. DNA from other closely related Mycoplasma species, as well as from a variety of other common urogenital organisms did not amplify in this multiplex PCR.
All 12 organisms included in the analytical specificity
panel were urease positive following four hours incubation so did not require for the broths to be re-incubated.
As the use of prophylactic HPV vaccines becomes more widespread, surveillance for population-levels of effectiveness is becoming an increasingly important activity, which requires the use of standardized HPV genotyping tests with analytical performance different from tests with clinically validated cutoffs; for example, tests with higher analytical sensitivity and absolute analytical specificity
Validation of the product, with 250 priorly characterised samples, demonstrated 100% identification of 3,025 known variants and an analytical specificity