analytical sensitivity

analytical sensitivity

The concentration at which the mean response is statistically beyond the noise limits of the signal at zero concentration. Analytical sensitivity is the ability of a test to detect a target analyte (e.g., an antibody or antigen), which is usually expressed as the minimum detectable concentration of the analyte. In practice, the way in which analytic sensitivity is calculated varies according to the lab, with differing replicates and matrices.
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We have achieved preliminary performance data for TRUFORMA canine eACTH with analytical sensitivity (< 9 pg/mL) and expect that the accuracy and time to result will be 16 minutes or less.
Taking both speed and accuracy into account, Zomedica noted preliminary performance data for TRUFORMA(TM) canine eACTH with analytical sensitivity (< 9 pg/mL) and expect that the accuracy and time to result will be 16 minutes or less.
Analytical sensitivity of TIBC, iron was 1.8umol/L and 0.9umol/L respectively while recovery is 95% and 97% respectively.
The preliminary data demonstrates effective detection of the most prevalent central nervous system pathogens with high analytical sensitivity and specificity levels, including the discrimination of clinically relevant strains and subtypes, the company said.
accuracy, precision, analytical sensitivity, specificity including interfering substances) and other performance characteristics for use in their patient populations, and meet the additional CLIA regulatory requirements for high-complexity testing as well as any applicable state regulations.
Based on the WCMD's AV history since its inception, Fitch's analytical sensitivity tool (FAST) generates a 1% scenario decline.
DiaCarta said the analytical sensitivity ranges from 0.1 to 0.5% for variant allelic frequency, providing lower detection limit compared with competition due to application of DiaCarta's proprietary XNA technology.
The sensitivity of each primer/probe is represented by the Ct, where the lower the value the higher the analytical sensitivity. Among all primers/probes, ZIKV D, designed by Pyke and coworkers (8), is the one that had the lowest Ct values followed by ZIKV E, while ZIKV C, designed by Tappe and coworkers (9), had the highest Cts, showing a very low analytical sensitivity.
Furthermore, the analytical sensitivity of HRMS configurations, often requiring a threshold to be reached, may preclude detection of SCs, which are often present at low- or sub-nanogram per milliliter concentrations in biological fluids.
Natera says that Vistara has a combined analytical sensitivity of >99% and a combined analytical specificity of >99% in validation studies.

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