analogue insulin

analogue insulin

A term of art for a synthesised insulin in which insulin’s amino acid sequence is altered by genetic engineering to alter absorption, delivery (e.g., to reduce clumping) or provide another desired characteristic.

Examples
Humulin (rapid absorption), Glargine (constant release over 24 hours).
 
Results
Evidence-based assessment indicates that they are much more expensive and do not substantially improve outcomes.
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References in periodicals archive ?
The decision applies to both IDeg alone and IDeg combined with the fast-acting insulin analogue insulin aspart.
Analogue insulin is modified to provide a slow, steady absorption over 24 hours.
The newer analogue insulin is significantly more expensive than the older isophane: $94.
Analogue insulin preparations were developed to mimic endogenous insulin secretion.
The analogue insulins tend to have flatter profiles while NPH peaks at 4 hours.
Comparison of the soluble basal insulin analogue insulin detemir with NPH insulin.
For boluses before meals, the short-acting analogue insulin lispro (Humalog, Eli Lilly & Go.
The advantages that a dual release analogue insulin offers us is that we can now design therapies to fit the patient and their lifestyle instead of forcing the patient to adjust to the therapy," said Dr Nattrass.
Despite the more complex production process and regulatory requirements for biosimilars, they offer a price reduction of between 35% and 50% of the parent insulin and analogue insulins.
Actavis and Bioton (WSE:BIO) announced today that they have formed a joint venture company for the development and registration of insulins, including analogue insulins.
Are analogue insulins better than soluble in continuous subcutaneous insulin infusion?
But because patients taking a combination of human and analogue insulins had been excluded from the study, the glargine patients were using much lower overall doses than were those on human insulin (median 22 vs.