analogue insulin

A term of art for a synthesised insulin in which insulin’s amino acid sequence is altered by genetic engineering to alter absorption, delivery (e.g., to reduce clumping) or provide another desired characteristic.

Examples
Humulin (rapid absorption), Glargine (constant release over 24 hours).

Results
Evidence-based assessment indicates that they are much more expensive and do not substantially improve outcomes.

References in periodicals archive ?

This has been done in development of the PEGylated version of the analogue insulin lispro which has been reported to be associated with a half-life of 2-3 days in people with type 2 diabetes [87].

Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

This observational study, PROGENS BENEFIT, aimed to compare efficacy, safety, and quality of treatment satisfaction of human and premixed analogue insulin among type 2 diabetic patients.

Efficacy, Safety, and Quality of Treatment Satisfaction of Premixed Human and Analogue Insulin Regimens in a Large Cohort of Type 2 Diabetic Patients: PROGENS BENEFIT Observational Study

Insulin is available in two forms human insulin and analogue insulin: Analogue insulin is produced by genetically altering human insulin to improve pharmacological properties such as speed of bioavailability.

Do we need insulin Analogue?

The newer analogue insulin is significantly more expensive than the older isophane: $94.50 for five vials of 3ml of 100u/ml, compared to $29.86.

Type 1 diabetes and insulin therapy

Consistent with previous reports, rapid acting analogue insulin delivered by itself via subcutaneous infusion exhibited significant variability in both absorption and action over three days of infusion set use.

Halozyme reports positive results from insulin pump trial

Time-action profile of the long-acting insulin analogue insulin glargine in comparison to NPH insulin in Japanese volunteers.

Insulin for intensifying diabetes treatment

Analogue insulin preparations were developed to mimic endogenous insulin secretion.

How to start and optimise insulin therapy: starting insulin therapy in type 2 diabetes can be challenging

and 10 p.m., as long as the short-acting analogue insulin lispro or insulin is taken before dinner and all other meals, Dr.

Lantus works best between 9 p.m. and 10 p.m. (With Adjuvant Humalog Before Meals)

The decision applies to both insulin degludec alone and combined with the fast-acting insulin analogue insulin aspart.

FDA withholds insulin degludec approval; wants safety data

The decision applies to both IDeg alone and IDeg combined with the fast-acting insulin analogue insulin aspart.

FDA wants safety data before degludec approval

Zaman Sheikh said that Analogue Insulin are also available in the markets which controls sugar after diet.