In the cashew nut shell, cashew nut shell liquid occurs mainly as anacardic acid
(~90%) and cardol around slightly lower than 10%.
Harris et al., "Anacardic acid
inhibits the catalytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9," Molecular Pharmacology, vol.
Reducing effect of dietary anacardic acid
on body fat pads in rats.
(20) The primary component of cashew nut liquid is anacardic acid
, which can be converted to cardanol by thermal decarboxylation.
This oil is mainly composed of anacardic acid
(3-n-pentadecylsalicylic acid), cardanol (3-n-pentadecylphenol), cardol (5-n pentadecylresorcinol), and methylcardol (2-methyl-5-npentadecylresorcinol).
In fact, it is known to contain a significant amount of anacardic acid
which is active against gram-positive bacteria (KUBO et al., 1993).
 revealed the effect of phytochemical and the antimicrobial activity of anacardic acid
which had an inhibitory effect on Staphylococcus aureus, Brevibacterium ammoniagenes, Streptococcus mutans, and Propionibacterium acnes.
Reddy, "Synthesis of isonicotinoylhydrazones from anacardic acid
and their in vitro activity against Mycobacterium smegmatis" European Journal of Medicinal Chemistry, vol.
, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549 [v1; ref status: indexed, http://f1000r.es/o7]
Many acids like formic acid, butyric acid, anacardic acid
, acetic acid and hydrochloric acid are found effective in controlling avian coccidiosis (Shobha and Ravindranath, 1991; Garcia et al., 2007; Abbas et al., 2011b, c).
It also acts as an astringent and cauterizing agent due to the phenolic skin stimulant (anacardic acid
) found mostly in the skin of the fruit, but also in the fruit itself .