amyloid-beta peptide

(redirected from amyloid-b peptide)

amyloid-β peptide

major neurotoxic component of extracellular deposits found in patients with Alzheimer disease.
References in periodicals archive ?
In their current work, the researchers at the RIKEN Brain Science Institute focused on AB43, an amyloid-B peptide found just as often in patient brains as AB42, but about which relatively little is known.
One hypothesis that has attracted widespread support proposes that AD is caused by the buildup of the senile plaques, and in particular of their main constituent, amyloid-B peptides (AB).
The biological mechanism may have to do with fat's impact on amyloid-B peptide deposits in the brain.