NYSE: PFE) has published a new interim analysis of long-term data from four studies indicating that treatment with tafamidis is associated with delay in disease progression in patients with hereditary transthyretin
amyloid polyneuropathy (TTR-FAP) and was well tolerated, with no unexpected side effects, the company said.
FAP, also known by Transthyretin (TTR) Amyloid Neuropathy or even Transthyretin (TTR)
Amyloid Polyneuropathy (since the three terms are considered synonyms) is a progressive sensorimotor and autonomic neuropathy of adulthood (Adams, 2013) and is caused by mutations in the TTR gene (18q12.
We present the first case of familial
amyloid polyneuropathy (FAP) type IV in an Iranian woman with severe involvement of multiple cranial nerves, peripheral limb neuropathy, and orthostatic hypotension.
This report provides comprehensive information on the therapeutic development for Familial
Amyloid Polyneuropathy (Transthyretin Amyloidosis, Corino de Andrade's Disease), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
Clinical and genetic analysis of three families with familiar
amyloid polyneuropathy.
A snapshot of the global therapeutic scenario for Familial
Amyloid Polyneuropathy (Transthyretin Amyloidosis, Corino de Andrade's Disease).
Changes in renal function in patients with familial
amyloid polyneuropathy treated with orthotopic liver transplantation.
Usefulness of MALDI/TOF mass spectrometry of immuno-precipitated serum variant transthyretin in the diagnosis of familial
amyloid polyneuropathy.
Surgeons will transplant part of the liver of a healthy 45-year-old man into his 42-year-old wife from Nagano who is suffering from a metabolic disorder known as familial
amyloid polyneuropathy (FAP), doctors said.
According to the transplant team, led by Yukihiro Inomata, a professor at the university in Kumamoto, Kumamoto Prefecture, the father has familial
amyloid polyneuropathy (FAP), a slowly progressive disease that can be fatal.
announced the publication of a new post-hoc analysis of data from three studies of VYNDAQEL in patients with mild transthyretin familial
amyloid polyneuropathy (TTR-FAP).
