Insulin and
amylin were found to have a similar influence on serum sRAGE profiles in AD, but
amylin was of special interest due to its ability to colocalize with A[beta] plaques in AD [36].
Raleigh, "Analysis of
amylin cleavage products provides new insights into the amyloidogenic region of human
amylin," Journal of Molecular Biology, vol.
The mammalian calcitonin gene-related peptides, adrenomedullin,
amylin, and calcitonin receptors.
Pramlintide, which is an analog of a natural occurring peptide,
amylin, produced by the pancreas, can easily cross the blood/brain barrier and has shown favorable safety profile for diabetes patients, she added.
It planned to finance the deal with existing cash and debt, according to an earlier statement.Today, Bristol-Myers Squibb said it would delist
Amylin as soon as possible and convert it into its fully-owned unit.
On Friday, London-based AstraZeneca (NYSE: AZN) , which is making a comeback as a leading pharmaceutical player, said it would pay $3.4 billion to
Amylin Pharmaceuticals following the Bristol-Myers acquisition.
Amylin Agonists:
Amylin is a peptide hormone that is co-secreted with insulin from the pancreatic ss-cell and is thus deficient in diabetics.15 It inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent.
Amylin shares closed the week down $9.74, or 46%, at $11.30.
This study ("
Amylin reduces plasma glucagon concentration in cats," The Veterinary Journal, 2010) was the first to investigate if
amylin reduces plasma glucagon levels in cats.
The drug is manufactured by
Amylin Pharmaceuticals, San Diego, CA, and Eli Lilly and Company, Indianapolis, IN.
23 July 2009 - Citigroup confirmed today its "buy" advice with a DKK330 share price target on Novo Nordisk A/S (CPH: NOVO B), despite some concerns raised by the sales figures of US rival
Amylin Pharmaceuticals Inc (NASDAQ: AMLN).
Amylin Pharmaceuticals (a company based in San Diego, California) has developed BYETTA (exenatide) injections, which is an approved treatment for type 2 diabetes that is injected subcutaneously twice a day.
