amylin


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Related to amylin: Symlin

am·y·lin

(am'i-lin),
A 37-amino acid peptide that is cosecreted with insulin from the pancreatic β-cell. Many of its biologic activities mimic those of calcitonin gene-related peptide, which is not a β-cell peptide. In patients with Type 1 diabetes, amylin is essentially absent from the plasma. The plasma level of amylin rises after a meal or a glucose load.
[amyloid + -in]

amylin

(ăm′ə-lĭn)
n.
1. A peptide hormone that is secreted along with insulin by the beta cells of the pancreas and helps to regulate blood sugar levels by inhibiting glucagon secretion and by slowing the rate at which food leaves the stomach.
2. Archaic Any of various components of starch.

amylin

An older term for:
(1) (Pancreatic) islet amyloid polypeptide;
(2) Amylopectin.

am·y·lin

(am'i-lin)
The cellulose of starch; the insoluble envelope of starch grains.
References in periodicals archive ?
Insulin and amylin were found to have a similar influence on serum sRAGE profiles in AD, but amylin was of special interest due to its ability to colocalize with A[beta] plaques in AD [36].
Raleigh, "Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin," Journal of Molecular Biology, vol.
The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.
Pramlintide, which is an analog of a natural occurring peptide, amylin, produced by the pancreas, can easily cross the blood/brain barrier and has shown favorable safety profile for diabetes patients, she added.
It planned to finance the deal with existing cash and debt, according to an earlier statement.Today, Bristol-Myers Squibb said it would delist Amylin as soon as possible and convert it into its fully-owned unit.
On Friday, London-based AstraZeneca (NYSE: AZN) , which is making a comeback as a leading pharmaceutical player, said it would pay $3.4 billion to Amylin Pharmaceuticals following the Bristol-Myers acquisition.
Amylin Agonists: Amylin is a peptide hormone that is co-secreted with insulin from the pancreatic ss-cell and is thus deficient in diabetics.15 It inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent.
Amylin shares closed the week down $9.74, or 46%, at $11.30.
This study ("Amylin reduces plasma glucagon concentration in cats," The Veterinary Journal, 2010) was the first to investigate if amylin reduces plasma glucagon levels in cats.
The drug is manufactured by Amylin Pharmaceuticals, San Diego, CA, and Eli Lilly and Company, Indianapolis, IN.
23 July 2009 - Citigroup confirmed today its "buy" advice with a DKK330 share price target on Novo Nordisk A/S (CPH: NOVO B), despite some concerns raised by the sales figures of US rival Amylin Pharmaceuticals Inc (NASDAQ: AMLN).
Amylin Pharmaceuticals (a company based in San Diego, California) has developed BYETTA (exenatide) injections, which is an approved treatment for type 2 diabetes that is injected subcutaneously twice a day.