amplification


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Related to amplification: DNA amplification

amplification

 [am″plĭ-fĭ-ka´shun]
the process of making larger, such as the increase of an auditory or visual stimulus, as a means of improving its perception.
DNA amplification artificial increase in the number of copies of a particular DNA fragment into millions of copies through replication of the segment into which it has been cloned, a type of nucleic acid amplification.
gene amplification a process by which the number of copies of a gene is increased in certain cells because extra copies of DNA are made in response to certain signals of cell development or of stress from the environment. In humans this process is seen most often in malignant cells.
nucleic acid amplification amplification of a specific nucleic acid sequence, such as to test for presence of a given virus or bacteria in a sample. Types include DNA amplification, ligase chain reaction, and polymerase chain reaction.

am·pli·fi·ca·tion

(am'pli-fi-kā'shŭn),
The process of making larger, as in increasing an acoustic or visual stimulus to enhance its perception.
[L. amplificatio, an enlarging]

amplification

(ăm′plə-fĭ-kā′shən)
n.
1. The act or result of amplifying, enlarging, or extending.
2. Physics
a. The process of increasing the magnitude of a variable quantity, especially the magnitude of voltage, power, or current, without altering any other quality.
b. The result of such a process.
3. Genetics The process by which extra copies of a gene or a DNA sequence are formed.

amplification

An in vivo (as in the fragile X syndrome) or in vitro (as in cloning or PCR) increase in the number of copies of a specific gene or DNA sequence of interest.

amplification

Molecular biology An in vivo–as in the fragile X syndrome or in vitro–as in cloning or PCR ↑ in the number of copies of a specific gene or DNA sequence of interest. See Cloning, DNA amplification, Exon amplification, Extreme amplification, Gene amplification, Linked linear amplification, PCR, PCR amplification of specific alleles, Solid phase amplification.

am·pli·fi·ca·tion

(am'pli-fi-kā'shŭn)
1. The process of making larger, as in increasing an auditory or visual stimulus to enhance its perception.
2. molecular biology Process of increasing the number of nucleic acid copies in a sample to millions within a short period.
[L. amplificatio, an enlarging]

amplification

The production of extra copies of a DNA sequence. These may be within the chromosomal sequence or outside it.

Amplification

A process by which something is made larger. In clotting, only a very few chemicals are released by the initial injury; they result in a cascade of chemical reactions which produces increasingly larger quantities of different chemicals, resulting in an appropriately-sized, strong fibrin clot.
Mentioned in: Hemophilia
References in periodicals archive ?
To assess the quality of the amplified signal and to verify that the LRA produced signal impairments have actually caused the above mentioned need for additional amplification, the dependence of BER values on the power of the detected signal in the channel with the highest BER was obtained both in the system with the LRA and in the system with the FOPA.
Loop-mediated isothermal amplification assays for detecting shiga toxin-producing Escherichia coli in ground beef and human stools.
Five (upper panel), 4--(middle panel) and 3--(lower panel) primer pair MLVA amplifications produced similar clustering for 16 MRSA strains isolated from the same medical centre in 2013.
2E depicts the amplification curves obtained with the 16-plex RAMP assay in the presence of 0, 1, 5, 50, and 500 PFU of the American ZIKV.
And on this basis the amplification of the acceleration along the free face of loess slope was studied as well.
Our results revealed the positive reaction was highly specific only with fresh blood samples containing XY chromosomes, while no amplification was found in blood samples containing XX chromosomes.
Fibroblast Growth Factor Receptor 1 Amplification in Nonsmall Cell Lung Cancer Epidemiology
The displacement amplification mechanism is the core component of the differential amplifying micro actuator.
Loop-mediated isothermal amplification (LAMP): Early detection of Toxoplasma gondii infection in mice.
Some studies concerning amplification of hTERT gene has been associated with cancer cell lines.
A related approach which also bypasses the need for nucleic acid amplification is FISH; as this was the subject of a recent (August 2015) installment of this series, we won't cover it in further detail here.