There were also ganglion-like cells with abundant
amphophilic to basophilic cytoplasm (Figure 4).
Necrotic neurons were variously swollen and hypereosinophilic or shrunken with tinctorial changes including faded,
amphophilic, or eosinophilic cytoplasm (Figure 5).
From low magnification, HGPIN is characterized by a distinctly basophilic appearance, a feature that is attributable to nuclear enlargement, overlapping, and hyperchromasia, as well as
amphophilic cytoplasm within the glands.
The predominant population of neoplastic cells were polygonal with distinct cell borders, a moderate amount of eosinophilic to
amphophilic lacy cytoplasm, and an irregularly round to oval nucleus possessing vesiculate chromatin and 1-2 prominent nucleoli.
Microscopically, classical EWS is composed of sheets of monotonous round to oval cells with round primitive-appearing nuclei and moderate amount of clear to
amphophilic cytoplasm.
Teratocarcinoma show large tumor cells with vesicular nuclei,
amphophilic cytoplasm, prominent nucleoli with calcification, and neural tissue.
Ductal features were defined as: (1) high-grade nuclei; (2) abundant and typically
amphophilic cytoplasm; and (3) tall/pseudostratified cells arranged in papillary projections, discreet glands, or cribriform structures with intervening slit like lumen.
Melatonin, being small and
amphophilic, distributes throughout all tissue components and fluids.
In histopathology, fibro vascular core is prominent and some large cells in stratum granulosum can display
amphophilic intranuclear inclusion body instead of nucleoli (Head et al.
ADV inclusions were defined by a homogeneous,
amphophilic, or basophilic mass that almost completely filled the nucleus.
The most striking pathologic findings in the excised specimen were seen in the subcutaneous tissue; there was extensive fat necrosis, with abundant amorphous eosinophilic and
amphophilic debris replacing, and interspersed between, adipocytes (FIGURE 3).
The sharply outlined cells will have finely granular cytoplasm that is either acidophilic,
amphophilic or clear (6-7) Typical features include oval and elongated nuclei, paranuclear inclusion bodies called "yellow bodies", acidophilic nuclear inclusions, fine nuclear grooving and infrequent mitotic figures (8) Whereas paragangliomas are well encapsulated and show typical nesting (zell-ballen) pattern, the tumor shows small to medium sized cells with granular
amphophilic cytoplasm.
