amphipathic

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am·phi·path·ic

(am'fē-path'ik),
Denoting a molecule, such as comprises detergents or wetting agents, which contains groups with characteristically different properties, for example, both hydrophilic and hydrophobic properties.
Synonym(s): amphiphilic, amphiphobic
[amphi- + G. pathos, feeling]

amphipathic

[-path′ik]
Etymology: Gk, amphi both + pathos suffering
pertaining to a molecule having two sides with characteristically different properties, such as a detergent, which has both a polar (hydrophilic) end and a nonpolar (hydrophobic) end but is long enough so that each end demonstrates its own solubility characteristics.

amphipathic

Of a chemical structure having both hydrophobic and hydrophilic surfaces as in the case of the phospholipid molecules of the cell membrane. Some proteins have amphipathic regions.

amphipathic

a molecule containing both HYDROPHILIC and HYDROPHOBIC components, as in a phospholipid molecule. See FLUID-MOSAIC MODEL.

amphipathic

molecules containing both polar and non-polar regions in their structure.
References in periodicals archive ?
Because 1-monocaproin is amphiphilic in nature and Generally Regarded as Safe and (GRAS), it could be a potent drug candidature targeting coronary artery disease, stroke, chronic wound, and wound-healing formulations in combination with the existing active drug molecules.
Water insoluble hydrophobic drugs can be encapsulated in amphiphilic PEG-PLA micelles either by physical entrapment method or by covalent chemical conjugation techniques [19].
Original antioxidant amphiphilic compounds for wood preservative formulations.
GO behaves like an amphiphilic macromoiecule with hydrophilic edges and a more hydrophobic basal plane, which makes it an attractive building block for the construction of various supramolecular architectures.
With pure CTP in hand, the folded structure of the peptide was assessed by Circular Dichroism (CD) spectroscopy in varying solvent conditions that served to mimic the amphiphilic cell surface microenvironment.
Capillary action and surface tension of liquids, amphiphilic surfactants, and monolayer lipid films are discussed, followed by parameters of adsorption and desorption at solid surfaces and wetting/cleaning processes.
Straub, Reverse Micelle: Biological and Technological Relevance of Amphiphilic Structure in Apolar Media, Plenium Press, New York, NY, USA, 1984.
Drug-induced lipidosis and vortex keratopathy is produced by amphiphilic medications such as amiodarone, chloroquine, suramin, clofazimine, etc16.
The first report described a method for solubilizing Qdots with random amphiphilic polymers and a demonstration of their uses in immunocytochemistry.
12, 2013), "Synthesis of Hyper-branched Amphiphilic Polyester and Theranostic Nanoparticles thereof," J.
Peptide-based block copolymers, biocompatible amphiphilic graft polyesters, polymers that can self-assemble into hierarchical nanostructures, lower critical solution temperature polymers, and supramolecular polymers containing cyclic oligomers are designed with the help of click chemistry.
Subsequent binding of C7 produces an amphiphilic complex (C5b-7) that has an affinity for cell membranes.