amphipathic


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am·phi·path·ic

(am'fē-path'ik),
Denoting a molecule, such as comprises detergents or wetting agents, which contains groups with characteristically different properties, for example, both hydrophilic and hydrophobic properties.
Synonym(s): amphiphilic, amphiphobic
[amphi- + G. pathos, feeling]

amphipathic

[-path′ik]
Etymology: Gk, amphi both + pathos suffering
pertaining to a molecule having two sides with characteristically different properties, such as a detergent, which has both a polar (hydrophilic) end and a nonpolar (hydrophobic) end but is long enough so that each end demonstrates its own solubility characteristics.

amphipathic

Of a chemical structure having both hydrophobic and hydrophilic surfaces as in the case of the phospholipid molecules of the cell membrane. Some proteins have amphipathic regions.

amphipathic

a molecule containing both HYDROPHILIC and HYDROPHOBIC components, as in a phospholipid molecule. See FLUID-MOSAIC MODEL.

amphipathic

molecules containing both polar and non-polar regions in their structure.
References in periodicals archive ?
Peptides'oncolytic effect depends on their cationic and amphipathic structure [8].
Cathelicidin AMPs are heterogeneous and share similar characteristics with other AMPs, such as a basic residue, overall amphipathic nature, and a net positive charge at neutral pH.
1959) The activation of surface films of lecithin by amphipathic molecules.
It is well known that sodium n-dodecyl sulfate (SDS), is an amphipathic anionic surfactant, employed widely in protein biochemistry for its powerful dissociation and solubilization properties.
It is assumed to be contributed to the large molecular weight, increased lipophilicity and an amphipathic nature of compounds but the exact mechanism is yet not known.
21 The proposed role of P-gp in the colon is to decrease the deposition of endogenous and exogenous hydrophobic amphipathic toxins.
Curvature is associated with asymmetry across the bilayer: this can be achieved by altering the types or amounts of lipids in one or both monolayers, inserting hydrophobic or amphipathic regions of proteins into the membrane, or applying external scaffolding forces (Graham and Kozlov, 2010).
7) It is this amphipathic behavior that can be used to disperse the oil slick.
y otros siete autores, Interaction with phospholipid bilayers: ion channel formation and antimicrobial activity of basic amphipathic a-helical model peptides of various chain lengths, J.
Amphipathic lipid metabolites and their relation to arrhythmogenesis in the ischemic heart.
SAA is one of the most important positive acute phase proteins, and an amphipathic apolipoprotein weighing 12 kDa.
Polymersomes are giant vesicles that are made from amphipathic block copolymers.