amphicrine tumour

amphicrine tumour

An older term for a neuroendocrine tumour (NET) characterised by dual differentiation of exocrine and endocrine cell features within the same cells.

Clinical findings
NETs present with vague, nonspecific symptoms, including abdominal pain, nausea, diarrhoea, weight loss, and rarely, obstructive symptoms; only 10% present with a carcinoid syndrome due to high circulating neuroendocrine hormones, in particular serotonin (5-HT), which causes flushing, diarrhoea, asthma and tricuspid regurgitation.