amorolfine


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amorolfine

A drug used externally in the treatment of TINEA infection of the skin. A brand name is Loceryl.

amorolfine

; Loceryl antifungal agent presented as a nail lacquer for daily topical application for 6 weeks at the early stage of white superficial onychomycosis or where only one or two nails are infected, or used topically in conjunction with systemic antifungal medication in cases with widespread mycotic nail infection

amorolfine

a morpholine derivative with antifungal activity.
References in periodicals archive ?
The function of laser therapy in this study was to render the nail more permeable to facilitate penetration of concurrent topical amorolfine to affected nails which was then evaluated.
10) Topical therapy options for onychomycosis include ciclopirox and amorolfine nail lacquers, and bifonazole-urea; these require application for prolonged periods of time.
5 Dermatophytes Amorolfine Efinaconazole Trichophyton rubrum 0.
It contains a biologically active agent selected from the group consisting of terbinafine, naftifine, amorolfine, butenafine, derivatives thereof, salts thereof, or combinations thereof; a delivery vehicle comprising a non-polymeric crystallization inhibitor that is capable of delaying crystallization of the biologically active agent, and a film-former; a volatile solvent in an amount selected to create a subsaturated solution of said biologically active agent; and water.
Amorolfine belongs to a new class of chemical antifungal.
The results of the comparative study regarding efficacy and safety of topical clotrimazole and amorolfine have already been published.
Sigurgeirsson and coworkers made the case for up-front combination therapy with amorolfine hydrochloride 5% nail lacquer and oral terbinafine for treating onychomycosis in patients with terbinafine monotherapy lack-of-cure risk factors.
CLEAR the problem directly by painting Curanail 5 per cent Nail Lacquer Amorolfine (pounds 18.
The new product, which contains amorolfine hydrochloride as an active ingredient, can exert beneficial effects with once-a-day dosage.
These investigators tested free-drug concentrations--in suspensions prepared from keratin samples--of efinaconazole, ciclopirox, and amorolfine (similar to ciclopirox, amorolfine is an agent in a lacquer formulation; amorolfine is not FDA-approved).
Local application of amorolfine paint (loceryl) is reported as curing 65% of limited distal nail infections 4 but the majority of people with tinea infections utilise over the counter preparations before presenting to their family doctor who may be poorly informed about foot disease and will rarely seek supportive mycological evidence of the causative organism.