amniotic band disruption sequence syndrome

amniotic band disruption sequence syndrome

an abnormal condition of fetal development characterized by the development of fibrous bands within the uterus that entangle the fetus, leading to deformities in structure and function. The syndrome is associated with a variety of congenital anomalies, including clubfoot, missing limbs, simian creases, and skull and visceral defects. It can be detected in the uterus. Interventions are specific to the varied symptoms, and genetic counseling is suggested.
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Amniotic bands

amniotic band disruption sequence syndrome

(am?ne-ot'ik)
Any of several fetal malformations associated with multiple fibrous strands of amnion that appear to develop or entangle fetal parts in utero. The disrupted sequence leads to structural malformations and deformations and disruption of function. The defects include limb defects and amputations; abnormal dermal ridge patterns; simian creases; clubbed feet; craniofacial defects, including cleft lip and palate; and visceral defects such as gastroschisis and omphalocele. Failure to understand the cause of this condition can lead to misdiagnosis and inappropriate family and genetic counseling.
See: multiple malformation syndrome