amlodipine


Also found in: Dictionary, Thesaurus, Wikipedia.
Related to amlodipine: Bisoprolol

amlodipine

 [am-lo´dĭ-pēn]
a calcium channel blocking agent administered orally in the form of the besylate salt in treatment of hypertension and chronic stable and vasospastic angina.

amlodipine

/am·lo·di·pine/ (am-lo´dĭ-pēn″) a calcium channel blocking agent used as the besylate salt in the treatment of hypertension and chronic stable and vasospastic angina.

amlodipine

[amlō′dipēn]
a calcium channel blocker administered orally in the form of the besylate salt in the treatment of hypertension and chronic stable and vasospastic angina.

amlodipine

A drug used in the treatment of ANGINA PECTORIS and high blood pressure (HYPERTENSION). A brand name is Istin.

amlodipine

calcium channel-blocking agent with similar actions to nifedipine (see Table 1)
Table 1: Drug treatment of hypertension
Drug typeExamplesComments
Thiazide diureticsBendroflumethiazide
Chlortalidone (Hygroton)
Cyclopenthiazide (Navidrex)
Indapamide (Natrilix)
Metolazone (Metenix 5)
Xipamide (Diurexan)		Indicated for hypertension in elderly patients
Tend to exacerbate diabetes, gout, systemic lupus erythematosus
May cause postural hypotension
Beta-blockers ('.…lol')Propranolol (Inderal)
Acebutolol (Sectral)
Atenolol (Tenormin)
Bisoprolol (Cardicor)
Carvedilol (Eucardic)
Celiprolol (Celectol)
Esmolol (Brevibloc)
Labetalol (Transdate)
Metoprolol (Betaloc)
Nadolol (Corgard)
Nebivol (Nebilet)
Oxprenolol (Trasicor)
Pindolol (Visken)
Sotalol (Beta-Cardone)
Timolol (Betim)		Should not be used by patients with asthma or bradycardia or hypotension
Should be avoided in patients with a history of Raynaud's
May cause distal paraesthesia, impotence, dizziness and exacerbation of psoriasis
Angiotensin-converting enzyme (ACE) inhibitors ('..…pril')Captopril
Cilazapril (Vascace)
Enalapril (Innovace)
Fosinopril (Staril)
Imidapril (Tanatril)
Lisinpril (Carace; Zestril)
Moexipril (Perdix)
Perindopril (Coversyl)
Quinapril (Accupro)
Ramipril (Tritace)
Trandolapril (Gopten)		Used only with care in patients taking diuretics, or those with peripheral vascular disease, generalized atherosclerosis and kidney disease
May cause profound hypotension, persistent cough, renal impairment, angioedema and pruritic rashes
Angiotensin II receptor antagonists ('.…sartan')Candesartan (Animax)
Eprosartan (Teveten)
Irbesartan (Aprovel)
Losartan (Cozaar)
Olmesartan (Olmetec)
Telmisartan (Micardis)
Valsartan (Diovan)		Used only with caution in patients with aortic or mitral valve stenosis, or renal artery disease
Tend not to be effective in Afro-Caribbean patients with left ventricular hypertrophy
Calcium-channel blockers ('.…dipine')Amlodipine (Istin)
Diltiazem (Calcicard)
Felodipine (Plendil)
Isradipine (Prescal)
Lacidipine (Motens)
Lercadidipine (Zanidip)
Nicardipine (Cardene)
Nifedipine (Adalat)
Nimodipine (Nimotrop)
Nisoldipine (Syscor MR)
Verapamil (Cordilox)		May cause abdominal pain, nausea, flushing, oedema, headache, dizziness, constipation and sleep disturbance
Alpha-blockers ('.…zosin')Doxazosin (Cardura)
Indoramin (Baratol)
Prazosin (Hypovase)
Terazosin (Hytrin)		Should not be used in patients with urinary incontinence
Tend to cause hypotension, dizziness, vertigo, headache, fatigue

Where antihypertensive drugs are used in combination, a rule-of-thumb guide indicates:

A + C (ACE inhibitors + calcium channel blockers)

B + D (beta-blockers + diuretics)

Mentioned in ?
References in periodicals archive ?
To determine whether a random steady-state plasma amlodipine concentration and Z-FHL/HHL ratio in the clinic setting could independently indicate adherence to medication for BP control.
Therapeutic drug monitoring of amlodipine and the Z-FHL/HHL ratio: adherence tools in patients referred for apparent treatment-resistant hypertension
The US Food and Drug Administration (FDA) approved the Indian pharma firms's abbreviated new drug application (ANDA) for Olmesartan Medoxomil and Amlodipine tablets for the treatment of hypertension, alone or with antihypertensive agents to lower blood pressure.
FDA approves Alembic Pharmaceuticals' ANDA for Olmesartan Medoxomil and Amlodipine tablets
Purpura, bleeding, calcium channel blockers, amlodipine.
Purpura and bleeding due to calcium channel blockers: A preliminary study
Conclusion: The combination therapy of valsartan with amlodipine significantly lowers the albuminuria in chronic Kidney disease and reduce the progression of disease as compared to Valsartan alone therapy.
To compare anti-albumin urea effects of valsartan alone with combination of valsartan and amlodipine in patients of chronic kidney disease
The aim of this study was to determine whether the GNB3 C825T polymorphism can influence antihypertensive response to amlodipine and telmisartan monotherapy in Chinese EH patients.
Influence of G-protein [beta]-Polypeptide 3 C825T Polymorphism on Antihypertensive Response to Telmisartan and Amlodipine in Chinese Patients
Amlodipine significantly changed all the three IOP and SBP parameters.
Glaucoma with hypertension: a comparison of treatment modality
Amlodipine is given in the dose of 5-10 mg once daily as it has a long duration of action.
Prevalence of gingival hyperplasia secondary to amlodipine
After administration of a single dose of amlodipine to 4 groups of animals the mice were subjected to electro-convulsions (each group with a constant current intensity ranging between 5 - 9 mA), the threshold for maximal electro-convulsions was recorded for 3 different doses of amlodipine (5, 10 and 20 mg/kg).
Effect of amlodipine on the antiepileptic action of lamotrigine, gabapentin & topiramate on maximal electroshock induced seizures in mice
The patient was hypertensive since 1 year and was under medication atenolol 50 mg and amlodipine 5 mg once daily.
Non-surgical management of a case of Amlodipine-induced gingival enlargement
There have been several studies comparing the antihypertensive efficacy and tolerability of a fixed combination of losartan (LST) and hydrochlorothiazide (HCTZ) with those of amlodipine besylate (AMLO) in westerners.
A comparative evaluation of Losartan/Hydrochlorothiazide (fixed combination) versus Amlodipine monotherapy in patients with hypertension in Rohilkhand region
Previous smaller-scale studies have reported that blood pressure drugs help lower the risk of dementia, but the new study will specifically test the effects of Amlodipine.
4pence-a-day BP pills can be effective in treating dementia
Within the normal-weight category, benazepril plus amlodipine was associated with significantly decreased risk for the composite endpoint (HR, 0.
What matters: basing hypertension treatment on BMI

Medical browser ?
Full browser ?