amiodarone-induced thyrotoxicosis

amiodarone-induced thyrotoxicosis

Cardiology Thyroid disease caused by amiodarone, an iodine-rich antiarrhythmic, which occurs in up to ±10% of amiodarone recipients living in areas of moderate iodine deficiency. See Thyrotoxicosis.
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Amiodarone-induced thyrotoxicosis type 2: a case report and review of the literature.
Christ et al., "Total thyroidectomy for amiodarone-induced thyrotoxicosis in the hyperthyroid state," Experimental and Clinical Endocrinology & Diabetes, vol.
(2) Adjuvant Treatment for Type 1 Amiodarone-Induced Thyrotoxicosis. Lithium is not the first-line treatment of type 1 amiodarone-induced thyrotoxicosis (AIT) [32], but few studies have used lithium as adjuvant treatment.
Patients with preexisting heart failure, atrial fibrillation/atrial flutter, cardiomyopathy, significant mitral valve disease, congenital heart disease, amiodarone-induced thyrotoxicosis, and subclinical hyperthyroidism were excluded.
Also, it has been indicated that full thyroidectomy may reinstate euthyroidism, thus refining heart function in patients of amiodarone-induced thyrotoxicosis with serious LV dysfunction [16].
Amiodarone-induced thyrotoxicosis (AIT) is commonly due to iodine-induced excessive synthesis of thyroid, also known as type 1 AIT (AIT1).
Amiodarone-induced thyrotoxicosis presenting as hypokalemic periodic paralysis.
The effects of plasmapharesis on thyroid hormone and plasma drug concentrations in amiodarone-induced thyrotoxicosis. Br J Clin Pharmacol 1991; 31: 371-2.
A stepwise approach to the treatment of amiodarone-induced thyrotoxicosis. Thyroid.
We describe the effects of iopanoic acid on daily levels of free triiodothyronine ([FT.sub.3]) and free thyroxine ([FT.sub.4]) in a patient with progressive type II amiodarone-induced thyrotoxicosis (AIT) who was undergoing thyroidectomy.
Thyroidologists have become so destructive that some of them recommend radioiodine ablation of the thyroid to allow the reintroduction of the toxic, organic iodine-containing drug, amiodarone in patients with a prior history of amiodarone-induced thyrotoxicosis. To quote Hormida, (28) et al: "...
More recently, perchlorate has been used (alone or in combination with other antithyroid drugs) to treat amiodarone-induced thyrotoxicosis or hypothyroidism, conditions in which underlying thyroid abnormalities are unmasked when the iodine-containing drug amiodarone is given to control cardiac arrhythmia (9).