aminotransferase


Also found in: Dictionary, Thesaurus, Financial, Encyclopedia.

transaminase

 [trans-am´ĭ-nās]
any of a group of enzymes that catalyze the reversible transfer of an amino group from a donor, usually an amino acid, to an acceptor, usually a 2-keto acid. Most use pyridoxal phosphate as a coenzyme.

a·mi·no·trans·fer·ase

(ă-mē'nō-trans'fĕr-ase),
Enzyme that transfers amino groups from an amino acid to a keto acid, for example, l-alanine and 2-ketoglutarate. Often, the amino acid is an α-amino acid and the keto acid is an α-keto acid.
Synonym(s): transaminases

aminotransferase

(ə-mē′nō-trăns′fə-rās′, -rāz′, ăm′ə-)

a·mi·no·trans·fer·ase

(ă-mē'nō-trans'fĕr-ās)
[EC sub-group 2.6.1] Enzyme transferring amino groups between an amino acid to (usually) a 2-keto acid.
Synonym(s): aminopherase, transaminase.

aminotransferase

see TRANSAMINASE.
References in periodicals archive ?
Xiao G, Yang J, Yan L.Comparison of diagnostic accuracy of aspartate aminotransferase to platelet ratio index and fibrosis-4 index for detecting liver fibrosis in adult patients with chronic hepatitis B virus infection: a systemic review and meta-analysis.Hepatology 2015; 61(1): 292-302.
In order to best guide clinician management on biopsies from patients with elevated aminotransferase levels and no symptoms, it is helpful to understand the decision-making process that led to the liver biopsy.
It is well known that prolonged elevation of aminotransferases (ATs) is often suggestive of acute and chronic hepatic diseases (1).
(ii) In the DQ class, 744 patients benefited from aminotransferase determination.
In patients with dystrophinopathy, the elevated levels of CK and aminotransferases can vary with age and other factors, such as genotype, clinical phenotype, and motor function, all of which made it difficult to establish applicable baselines of CK and aminotransferase levels for diagnostic purposes [43].
In 2 patients with DON and a past medical history of viral hepatitis B, the level of aminotransferases was within the normal range before and during therapy.
Effects of obstructive sleep apnea syndrome on serum aminotransferase levels in obese patients.
Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1,585 cases.
HCV: hepatitis C virus; AST: aspartate aminotransferase; ALT: alanine aminotransferase; AAR: aspartate aminotransferase to alanine aminotransferase ratio; PT: prothrombin time; INR: international normalized ratio; RDW: red cell distribution width; APRI: aspartate aminotransferase-to-platelet ratio index; FIB-4: fibrosis index based on the 4 factors; RPR: red cell distribution width to platelet ratio; PLR: platelet-lymphocyte ratio.
Predisposing factor AST ALT Bilirubin (U/L) (U/L) (mg/dL) Case 1 Crohn's- immuno- suppression, 9378 3510 7.4 steroids Case 2 Pregnancy 4559 998 21.7 (2nd trimester) Case 3 Liver transplant- immunosuppres- sion, 780 712 1.9 steroids Platelets INR GFR Outcome (x [10.sup.3] (mL/min/ /[micro]L).sup.4] [m.sup.2]) Case 1 130 2.1 42 Survived Case 2 33 5.1 30 Died Case 3 107 1.3 96 Survived ALT: alanine aminotransferase; AST: aspartate aminotransferase; INR: international normalized ratio; GFR: glomerular filtration rate.
The VetScan with Avian/Reptilian Profile Plus rotors reports concentrations of the following analytes: albumin, aspartate aminotransferase, bile acids, calcium, creatine kinase, globulin, glucose, phosphorus, potassium, total protein, sodium, and uric acid.