naphthophila RKU-10 confirmed this cellulase as a member of M42 Family of aminopeptidases
The activity of Leucine aminopeptidase
was determined using the method of Maraux et al.
Fruci, "Role of endoplasmic reticulum aminopeptidases
in health and disease: from infection to cancer," International Journal of Molecular Sciences, vol.
In lepidopteran larvae, aminopeptidase
N (APN) is one of at least 4 Cry1A protein-binding toxins (Bravo et al.
LNPEP, the gene which encodes the [AT.sub.4] receptor, but which may have a more important cellular function as insulin-regulated aminopeptidase
, was also expressed at a low level and its expression did not differ between normal lung tissue and lung tumor tissue.
These peptides are further trimmed by aminopeptidases
ERAP to enable optimal peptide loading onto MHC class I molecules.
Vanha-Perttula, "Characterization of three aminopeptidases
purified from maternal serum," Biochimica et Biophysica Acta (BBA)--Protein Structure and Molecular Enzymology, vol.
It is believed that the tendency is genetically determined and related to polymorphic variants in genes that modulate the activity of aminopeptidases
This modification protects it against aminopeptidase
degradation, and improves receptor activation and signal transduction in vitro (11).
Enzyme activity was virtually unaffected when light organ homogenates were incubated with a protease inhibitor cocktail containing inhibitors specific to serine, cysteine, aspartic, and aminopeptidases
, but no MMP inhibitors; however, this cocktail markedly reduced the gelatinase activity of digestive gland homogenates.
catalyse the cleavage of amino acids from the amino-termini of protein or peptide substrates (8).
, Varmanen et al.,  and Varmanen et al.,  have isolated proteolytic species of Lactobacillus such as Lactobacillus bulgaricus and Lactobacillus rhamnosus with aminopeptidases
and prolinase activity.