Biochemical studies reveal significant decrease in the enzyme activities like glucose-6-phosphatase, alkaline phosphatase, ATPase and succinic acid dehydrogenase, aminolevulinic acid dehydratase
and cholinesterase activities and moderate increases of acid phosphatases activity in the liver, kidneys and brain of laboratory animals and malonic dialdehyde levels in the kidneys of rats after mercury intoxication (Taylor at al.
Succinylacetone is an inhibitor of the heme synthesis pathway, causing neurotoxicity that is similar to lead poisoning or aminolevulinic acid dehydratase
(ALAD) deficiency porphyria (Wyllie & Hyams, 2006).
259) hypothesized that associations might be modified by a common variant allele of the aminolevulinic acid dehydratase
(ALAD) gene, which encodes the primary carrier protein for lead in blood.
OBJECTIVE: The main objective is to determine the role of the aminolevulinic acid dehydratase
(ALAD) gene, which encodes the main carrier protein of lead in blood, in the association between lead exposure and blood pressure (BP) and hypertension in the U.
Aminolevulinic acid dehydratase
genotype mediates plasma levels of the neurotoxin, 5-aminolevulinic acid, in lead-exposed workers.
Biochemical and immunological properties of hepatic aminolevulinic acid dehydratase
in channel catfish (Ictalurus punctatus).