aminoacyl-tRNA synthetases


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a·mi·no·ac·yl-tRNA syn·the·tas·es

enzymes catalyzing the formation of a specific aminoacyl-tRNA from an amino acid and adenosine 5'-triphosphate with the concomitant formation of adenosine 5'-monophosphate and pyrophosphate.

tRNA

transfer RNA (ribonucleic acid).

aminoacyl-tRNA
transfer RNA to which its specific amino acid has been coupled by its specific aminoacyl-tRNA synthetase.
aminoacyl-tRNA binding site
one of two tRNA binding sites on a ribosome that holds the incoming tRNA molecule charged with an amino acid. Called also A site.
aminoacyl-tRNA synthetases
a set of enzymes that couple each of the 20 amino acids to its appropriate tRNA molecule.
initiator tRNA
a special methionine tRNA that binds to the initiation codon AUG that forms part of the initiation complex at the start of mRNA translation.
peptidyl-tRNA binding site
one of two tRNA binding sites on a ribosome that holds the tRNA that is normally linked to the polypeptide chain. Called also P site.
References in periodicals archive ?
EVALUATING THE INTERACTIONS BETWEEN AMINOACYL-tRNA SYNTHETASES AND ELONGATION FACTOR TU IN PROTEIN SYNTHESIS
Our data raise several evolutionary questions, and the first is about the aminoacyl-tRNA synthetases themselves.
The aminoacyl-tRNA synthetases help establish the rules of the genetic code, by mediating the translation of DNA to protein.
A novel proposed alignment of the aminoacyl-tRNA synthetases was found using this system.
Amino acids are covalently attached to their cognate tRNAs through the enzymatic action of aminoacyl-tRNA synthetases.