amiloride


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Related to amiloride: furosemide, Amiloride hydrochloride

amiloride

 [ah-mil´o-rīd]
a potassium sparing diuretic, used as the hydrochloride salt, usually in combination with hydrochlorothiazide, in the treatment of edema and hypertension and the prevention and treatment of hypokalemia.

amiloride

Nephrology A drug that blocks the Na+/H+ antiporter, used clinically as a potassium-sparing diuretic. See Diuretics, Potassium-sparing diuretic Pulmonology An aerosolized sodium channel blocker that may slow the progression of pulmonary dysfunction in cystic fibrosis. See Diuretics, Potassium-sparing diuretic.

amiloride

A thiazide DIURETIC drug that acts by reducing reabsorption of sodium, and thus water, in the kidneys. A potassium-sparing diuretic used in the treatment of high blood pressure (HYPERTENSION), HEART FAILURE or other conditions in which excess fluid is retained in the body. The drug is on the WHO official list. Formulated in combination with other drugs under brand names such as Amil-Co, Burinex A, Fru-Co, Frumil, Kalten, Lasoride, Moducren, Moduret 25, Moduretic and Navispare.
References in periodicals archive ?
Amiloride alone has never been registered in SA, but is available in a combination tablet with hydrochlorothiazide (HCTZ) (amiloride 5 mg, HCTZ 50 mg).
Amiloride restores renal medulary osmolytes in lithium-induced nephrogenic diabetes insipidus.
Following Not following Furosemide + 100% 0% Amiloride Furosemide + 100% 0% Spironolactone Furosemide 60% 40% Note: Table made from bar graph.
Sorts of interactions between lithium and different diuretics [a] [lithium] Thiazides and chlorthalidone, analogs hydrochlorothiazide, indapamide * Variable interaction Loop diuretics furosemide ([b] or [c] [lithium}) [K.sup.+]-sparing amiloride *, diuretics spironolactone *, triamterene * [d] [lithium] Osmotic diuretics mannitol, urea Carbonic anhydrase acetazolamide inhibitors * Scarce evidence/class effect assumed.
Mostafa, "HPLC and chemometric-assisted spectrophotometric methods for simultaneous determination of atenolol, amiloride hydrochloride and chlorthalidone," Il Farmaco, vol.
Abe, "Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor," Biochemical and Biophysical Research Communications, vol.
To test the photocatalytic activity of the catalysts, two organic compounds were used as the pollutant model, the methylene blue dye (maximum absorption at 554nm), and the amiloride drug (maximum absorption 286nm) (Figure 8).
Amiloride appeared to be weakly inductive to larvae of the hydroid Hydractinia echinata: a 600 [micro]mol [l.sup.-1] solution of amiloride in seawater induced ~30% of the tested larvae to metamorphose (Berking, 1988).
Potassium-sparing diuretics such as amiloride have been avoided because of perceived lack of BP-lowering efficacy and increased risk of hyperkalemia because of increasing use of RAS blockers.
Interestingly, amiloride reduces uPAR expression in rat podocytes, and this was associated with decreased podocyte motility and decreased proteinuria.
They are voltagein-sensitive, cation-selective channels that are mostly permeable to [Na.sup.+] and nonspecifically blocked by amiloride. Seven different subunits, 1a, 1b, 2a, 2b, 3, 4 and 5 (a and b refer to splice variants), derived from 5 genes (ACCN1-5) have been identified in mammals.
When renal function improved, valsartan and amiloride were prescribed and steroids discontinued.