amelogenin


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amelogenin

/am·e·lo·gen·in/ (-jen´in) any of several proteins secreted by ameloblasts and forming the organic matrix of tooth enamel.

amel·o·gen·in

(am'ě-lō-jen'in)
A class of proteins that form much of the organic matrix during the early development of tooth enamel.

amelogenin

A structural protein used as a drug to treat PERIODONTITIS. The drug is formulated as a gel that is placed under a flap in the gum surrounding the root of the tooth and promotes regrowth of gum tissue that has been destroyed by the inflammatory process. A brand name is Emdogain.
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47) In addition, concentrations of 120 [micro]M of F- reduce the expression of messengers of amelogenin, ameloblastin, enamelin, and MMP-20, as well as factors of vascularization, such as the endothelial growth factor (VEGF), monocyte chemoattractant proteins (MCP-1) and the interferon inducible protein (IP-10).
Evolution, Identification and characterization of amelogenin genes in monotremes, reptiles, and amphibians (tooth formationyevolutionary innovations).
6] Human genes: DMD, dystrophin (muscular dystrophy, Duchenne and Becker types); AMELX, amelogenin (amelogenesis imperfecta 1, X-linked); AMELY, amelogenin, Y-linked.
The gender indicator amelogenin can be eliminated from the printouts if there is concern about revealing a genotype that is inconsistent with phenotype, as in the rare case of androgen insensitivity syndrome (XY female).
Amelogenin interacts with cytokeratin 5 in ameloblast during enamel growth.
For years, researchers have had good reason to suspect that a protein called amelogenin contributes to the growth of enamel in gums.
3] was found to be able to regulate the expression of a tooth-specific gene: amelogenin gene (Papagerakis et al.
The amount of nucleic acids obtained, the success rate in the amplification of DNA microsatellite (STR) markers and amelogenin by PCR, the influence of PCR inhibitors and environmental conditions, and where the samples were found before their processing in the laboratory, were all evaluated in this investigation for the three methods.
A large imbalance between the X-allele and Y-allele at the amelogenin locus was observed in the two mixed profiles, confirming the presence of only a small amount of the perpetrator's DNA (Figure 2A).
The amelogenin nanospheres are thought to function less in apatite nucleation than in localizing and orienting the developing enamel crystallites prior to their maturation (Fincham et al.
The "police cooperation" group has agreed on the use of seven common DNA markers (in addition to amelogenin which reveals gender by marking the XY amelogenin gene).
Emdogain is a sterile protein mix of enamel matrix, amelogenin, and the precursor of enamel from developing teeth.