Rostral mandibulectomy for treatment of an ameloblastic
fibroodontoma in a cow.
Pathologic diagnosis: Benign tumors Diagnosis n (%) Hemangioma 5 (9) Ossifying fibroma 4 (7) Adnexal neoplasm 1 (2) Ameloblastic
fibro-odontoma 1 (2) Benign fibrous histiocytoma 1 (2) Blue nevus 1 (2) Compound nevus 1 (2) Epithelioma adenoides cysticum 1 (2) Giant cell granuloma 1 (2) Lymphangioma 1 (2) Neurofibroma 1 (2) Osteochondroma 1 (2) Port wine stain 1 (2) Spitz nevus 1 (2) Xanthogranuloma 1 (2) Total 22 (41) Table 4.
An incisional biopsy was done providing a diagnosis of ameloblastic
fibro-odontoma is a benign epithelial odontogenic tumor.
fibro odontoma is derived from odontogenic epithelium and pulpal mesenchyme.
2) Ameloblastomas arise in dentigerous cysts or in others in which the neoplastic ameloblastic
epithelium is preceded temporarily by a nonneoplastic stratified squamous epithelial lining.
The differential diagnosis for this entity includes ameloblastic
fibroma, squamous cell carcinoma and basal cell carcinoma.
Therefore, PIOSCC must be considered in the differential diagnosis of malignant tumors of odontogenic epithelium, including ameloblastic
carcinoma, clear cell odontogenic carcinoma, central mucoepidermoid carcinoma, odontogenic ghost cell carcinoma, and a malignant variant of calcifying epithelial odontogenic tumor.
Any apparent recurrence should raise suspicion of an ameloblastic
tumor, which requires more aggressive treatment.
In sections of the lesion, ameloblastic
elements and granulation tissue intermingled.
1) The ameloblastic
cells are columnar epithelial cells palisaded about the periphery of the tumor nests, with a subnuclear vacuolization away from the basement membrane.
In addition, less likely consideration included locally aggressive odontogenic lesions, such as ameloblastic
fibro-odontoma, as well as other entities consisting of calcifying odontogenic cyst (Gorlin cyst), adenomatoid odontogenic tumor, and primordial cysts (keratocyst).