A potential clinical clue to the diagnosis of amelanotic
melanoma may be the presence of a macular rim or spot of tan, gray, or brown pigmentation at the periphery of the lesion," Ms.
Neurocutaneous melanosis presenting with intracranial amelanotic
Paucivascular anaplastic KS needs to be distinguished from other high-grade sarcomas (eg, leiomyosarcoma, spindle cell rhabdomyosarcoma, malignant peripheral nerve sheath tumor, fibrosarcoma), amelanotic
spindle cell melanoma, and spindle cell carcinoma.
5,6] The appearance of tumors is almost always pigmented with only 10-20% being amelanotic
melanoma of the breast: combating a rare cancer [published online ahead of print October 27, 2010].
Vitiligo ponctue is rare; discrete, confetti-like amelanotic
macules occur on normal or hyperpigmented skin.
Metastatic carcinoma must always be considered in the differential diagnosis of a nonpigmented intraocular tumor and is usually a primary consideration in adults with medulloepithelioma along with amelanotic
HPE revealed "RARE AMELANOTIC
MALIGNANT MELANOMA" of the vaginal mucosa.
Such cases of amelanotic
melanoma in situ lack classical morphologic features and may thus easily elude clinical diagnosis.
forms do not seem to be rare in AMM; in those cases, the disease may go unsuspected even by the best clinician.
However, Spitz nevi are typically amelanotic
or exhibit lightly melanized cytoplasm.
30,31) However, CMC has a very common presentation as clinically amelanotic
lesions, (23,32) and 7% of melanomas that develop in association with a preexisting nevus are asymptomatic.