alveolar macrophage


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al·ve·o·lar mac·ro·phage

a vigorously phagocytic macrophage on the epithelial surface of lung alveoli where it ingests inhaled particulate matter.
Synonym(s): coniophage, dust cell

alveolar macrophage

A free mononuclear cell of the lower respiratory tract, which has a high phagocytic capacity and is responsible for clearing inhaled particles and lung surfactant. Alveolar macrophages (AMss,  are transiently attached by pseudopodia to the surface of alveolar epithelium. Presence of AMs in sputum submitted for cytologic evaluation are markers of specimen adequacy. AMs are generally submerged in a film of phospholipids, and thus form part of the surface lining of the aveoli.

alveolar macrophage

Physiology A free mononuclear cell of the lower respiratory tract, which has a high phagocytic capacity, and is responsible for clearing inhaled particles and lung surfactant; AMs are transiently attached by pseudopodia to the surface of alveolar epithelium; presence of AMs in sputum submitted for cytologic evaluation are markers of specimen adequacy; AMs are generally submerged in a film of phospholipids, and thus form part of the surface lining of the aveoli See Dust cell, Dust macule.

al·ve·o·lar mac·ro·phage

(al-vē'ŏ-lăr mak'rō-fāj)
A vigorously phagocytic macrophage on the epithelial surface of lung alveoli where it ingests inhaled particulate matter.
Synonym(s): coniophage, dust cell.

al·ve·o·lar mac·ro·phage

(al-vē'ŏ-lăr mak'rō-fāj)
A vigorously phagocytic macrophage on the epithelial surface of lung alveoli where it ingests inhaled particulate matter.
Synonym(s): coniophage, dust cell.
References in periodicals archive ?
Alveolar macrophages regulate neutrophil recruitment in endotoxin-induced lung injury.
Sethi, "Impaired phagocytosis of nontypeable Haemophilus influenzae by human alveolar macrophages in chronic obstructive pulmonary disease," The Journal of Infectious Diseases, vol.
Mukaro et al., "Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine," American Journal of Respiratory Cell and Molecular Biology, vol.
Further indicating that peroral arsenic has no overt effect on the local innate immune response of the airspace, alveolar macrophages harvested from arsenic-exposed and control mice after LPS inhalation generated equivalent TNF[alpha] ex vivo (Figure 4d).
It is important to realize, however, that the effects of alcohol on alveolar macrophage innate immune function are just one facet of the complex pathophysiology of alcohol and the lung's immune system.
Soukup, "Cytokine (tumor necrosis factor, IL-6, and IL-8) production by respiratory syncytial virusinfected human alveolar macrophages," Journal of Immunology, vol.
There are reported cell proliferations in the bronchi and bronchioles following nanoparticle inhalation [22, 23] and an accumulation of alveolar macrophages is also observed [4, 24].
When asbestos fibers penetrate and deposit on alveolar surfaces, alveolar macrophages attempt to engulf them and remove them from the site of deposition.
HIV-1-transgene expression in rats decreases alveolar macrophage zinc levels and phagocytosis.
Comparative analysis of the alveolar macrophage proteome in ALI/ARDS patients between the exudative phase and recovery phase.
The alveolar macrophage is an important immune cell affected by alcohol consumption.
Clouter, "Impairment of alveolar macrophage phagocytosis by ultrafine particles," Toxicology and Applied Pharmacology, vol.