alveolar macrophage


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al·ve·o·lar mac·ro·phage

a vigorously phagocytic macrophage on the epithelial surface of lung alveoli where it ingests inhaled particulate matter.
Synonym(s): coniophage, dust cell

alveolar macrophage

a cell of the reticuloendothelial system in the lungs that engulfs and digests foreign substances inhaled into the alveoli.

alveolar macrophage

A free mononuclear cell of the lower respiratory tract, which has a high phagocytic capacity and is responsible for clearing inhaled particles and lung surfactant. Alveolar macrophages (AMss,  are transiently attached by pseudopodia to the surface of alveolar epithelium. Presence of AMs in sputum submitted for cytologic evaluation are markers of specimen adequacy. AMs are generally submerged in a film of phospholipids, and thus form part of the surface lining of the aveoli.

alveolar macrophage

Physiology A free mononuclear cell of the lower respiratory tract, which has a high phagocytic capacity, and is responsible for clearing inhaled particles and lung surfactant; AMs are transiently attached by pseudopodia to the surface of alveolar epithelium; presence of AMs in sputum submitted for cytologic evaluation are markers of specimen adequacy; AMs are generally submerged in a film of phospholipids, and thus form part of the surface lining of the aveoli See Dust cell, Dust macule.

al·ve·o·lar mac·ro·phage

(al-vē'ŏ-lăr mak'rō-fāj)
A vigorously phagocytic macrophage on the epithelial surface of lung alveoli where it ingests inhaled particulate matter.
Synonym(s): coniophage, dust cell.

al·ve·o·lar mac·ro·phage

(al-vē'ŏ-lăr mak'rō-fāj)
A vigorously phagocytic macrophage on the epithelial surface of lung alveoli where it ingests inhaled particulate matter.
Synonym(s): coniophage, dust cell.
References in periodicals archive ?
Further indicating that peroral arsenic has no overt effect on the local innate immune response of the airspace, alveolar macrophages harvested from arsenic-exposed and control mice after LPS inhalation generated equivalent TNF[alpha] ex vivo (Figure 4d).
For example, zinc supplementation in experimental models of chronic alcohol ingestion improves redox balance, enhances Nrf2 binding in the nucleus, corrects alveolar macrophage immune dysfunction, and restores GM-CSF receptor expression and signaling, suggesting that one target can interact with several implicated pathways (Joshi et al.
Quantitative intact proteomics investigations of alveolar macrophages in sarcoidosis.
Kornfeld, "Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages," Journal of Immunology, vol.
Soukup, "Cytokine (tumor necrosis factor, IL-6, and IL-8) production by respiratory syncytial virusinfected human alveolar macrophages," Journal of Immunology, vol.
The speculation is alveolar macrophages deposit them there as the macrophages transport asbestos fibers through the lymphatic system after phagocytizing them in the alveoli.
HIV-1-transgene expression in rats decreases alveolar macrophage zinc levels and phagocytosis.
Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase1 by alveolar macrophages from patients with chronic obstructive pulmonary disease.
We used all three batches in the Western analyses of alveolar macrophages (autophagy markers and MAP kinases).
Early activation of the alveolar macrophage is critical to the development of lung ischemia reperfusion injury.
Lyn was found to be important for NFr, B mediated increased expression and release of macrophage chemotactic factors (MCP-1 secretion) that recruit alveolar macrophage (AM) to the site of infection.
Alcohol-induced defects in alveolar macrophage function and other components of the lung's innate immune defenses suggest that alcoholics cannot mount an appropriate response to infections, as evidenced by decreased levels of important molecules in the immune system (i.