aluminum hydroxide

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 (Al) [ah-loo´mĭ-num]
a chemical element, atomic number 13, atomic weight 26.982. (See Appendix 6.) It occurs naturally in many foods in low concentrations and is also present in many pharmaceuticals and drinking water. High levels in the body can be toxic; see aluminum poisoning.
aluminum acetate solution Burow's solution.
basic aluminum carbonate gel an aluminum hydroxide–aluminum carbonate gel, used as an antacid, for treatment of hyperphosphatemia in renal insufficiency, and to prevent phosphate urinary calculi.
aluminum chloride a topical astringent solution and antiperspirant.
aluminum chlorohydrate an antiperspirant; called also aluminum hydroxychloride.
aluminum hydroxide the hydroxide of aluminum, used as an antacid and phosphate binder; the official preparation is aluminum hydroxide gel.
aluminum hydroxide gel a preparation of aluminum hydroxide in suspension or dried form, used as an antacid in the treatment of peptic ulcer and gastric hyperacidity and as a phosphate binder in treatment of phosphate nephrolithiasis.
aluminum hydroxychloride aluminum chlorohydrate.
aluminum oxide Al2O3, occurring naturally as various minerals; used in the production of abrasives, refractories, ceramics, catalysts, to strengthen dental ceramics, and in chromatography.
aluminum phosphate gel a water suspension of aluminum phosphate and some flavoring agents; used as a gastric antacid, astringent, and soothing agent.
aluminum poisoning the toxic effects of high levels of aluminum or its compounds in the body. In the gastrointestinal tract aluminum inhibits absorption of electrolytes; inhalation of aluminum fumes may cause pulmonary fibrosis; and aluminum in the bloodstream may lead to serious neurological symptoms, such as in dialysis encephalopathy.
aluminum silicate the silicate salt of aluminum, found in nature in several different hydrated forms that have pharmaceutical or dental uses; see attapulgite, fuller's earth, and kaolin.
aluminum subacetate a compound used as an astringent, diluted with water.
aluminum sulfate a compound used as an astringent solution and antiperspirant.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

aluminum hydroxide

AlternaGEL, Alu-Cap, Alu-Tab

Pharmacologic class: Inorganic salt

Therapeutic class: Antacid

Pregnancy risk category NR


Dissolves in acidic gastric secretions, releasing anions that partially neutralize gastric hydrochloric acid. Also elevates gastric pH, inhibiting the action of pepsin (an effect important in peptic ulcer disease).


Capsules: 400 mg, 475 mg, 500 mg

Oral suspension: 320 mg/5 ml, 450 mg/5 ml, 600 mg/5 ml, 675 mg/5 ml

Tablets: 300 mg, 500 mg, 600 mg

Indications and dosages


Adults: 500 to 1,500 mg (tablet or capsule) P.O. 1 hour after meals and at bedtime; or 5 to 30 ml (oral suspension) between meals and at bedtime, as needed or directed

Off-label uses

• Bleeding from stress ulcers

• Gastroesophageal reflux disease


• Signs or symptoms of appendicitis or inflamed bowel


Use cautiously in:

• gastric outlet obstruction, hypercalcemia, hypophosphatemia, massive upper GI hemorrhage

• patients using other aluminum products concurrently

• patients on dialysis

• pregnant or breastfeeding patients.


• Administer with water or fruit juice.

• Give 1 hour after meals and at bedtime.

• In reflux esophagitis, administer 20 to 40 minutes after meals and at bedtime.

• Don't give within 1 to 2 hours of antibiotics, histamine2 (H2) blockers, iron preparations, corticosteroids, or enteric-coated drugs.

• Provide care as appropriate if patient becomes constipated.

Adverse reactions

CNS: malaise (with prolonged use), neurotoxicity, encephalopathy

GI: constipation, anorexia (with prolonged use), intestinal obstruction

Metabolic: hypophosphatemia (with prolonged use)

Musculoskeletal: osteomalacia and chronic phosphate deficiency with bone pain, malaise, muscle weakness (with prolonged use)

Other: aluminum toxicity


Drug-drug. Allopurinol, anti-infectives (including quinolones, tetracyclines), corticosteroids, diflunisal, digoxin, ethambutol, H2 blockers, hydantoins, iron salts, isoniazid, penicillamine, phenothiazines, salicylates, thyroid hormone, ticlopidine: decreased effects of these drugs

Enteric-coated drugs: premature release of these drugs in stomach

Drug-diagnostic tests. Gastrin: increased level

Phosphate: decreased level

Some imaging studies: test interference

Drug-food. Milk, other foods high in vitamin D: milk-alkali syndrome (nausea, vomiting, distaste for food, headache, confusion, hypercalcemia, hypercalciuria)

Patient monitoring

• Monitor long-term use of high doses if patient is on sodium-restricted diet. (Drug contains sodium.)

• Assess for GI bleeding.

• Watch for constipation.

• With long-term use, monitor blood phosphate level and assess for signs and symptoms of hypophosphatemia (anorexia, malaise, muscle weakness). Also monitor bone density.

Patient teaching

• Tell patient to take drug 1 hour after meals and at bedtime.

• Caution patient not to take drug within 1 to 2 hours of anti-infectives, H2 blockers, iron, corticosteroids, or enteric-coated drugs.

• Advise patient to take drug with water or fruit juice.

• Instruct patient to report signs and symptoms of GI bleeding and hypo-phosphatemia (appetite loss, malaise, muscle weakness).

• Recommend increased fiber and fluid intake and regular physical activity to help ease constipation.

• Inform patient that drug contains sodium, so he should discuss drug therapy with health care providers if he's later told to consume a low-sodium diet.

• Advise patient that he'll need to undergo periodic blood testing and bone mineral density tests if he's receiving long-term therapy.

• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, and foods mentioned above.

McGraw-Hill Nurse's Drug Handbook, 7th Ed. Copyright © 2013 by The McGraw-Hill Companies, Inc. All rights reserved

a·lu·mi·num hy·drox·ide

an astringent dusting powder; also used internally as a mild astringent antacid.
Farlex Partner Medical Dictionary © Farlex 2012

a·lu·mi·num hy·drox·ide

(ă-lūmi-nŭm hī-droksīd)
Astringent dusting powder; also used internally as a mild astringent antacid.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

a·lu·mi·num hy·drox·ide

(ă-lūmi-nŭm hī-droksīd)
Astringent dusting powder; also used internally as a mild astringent antacid.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Veneers treated with aluminum hydroxide showed weakening of peaks at 1730, 1660, and 1600 [cm.sup.-1], but the changes were less pronounced compared to those observed for wood treated with chromium trioxide or sodium aluminate.
Imports of aluminum hydroxide have tended to increase--from 69,786 tons valued at US$ 14.6 million in 1995 to 104,042 tons valued at US$ 17.61 million in 2002.
Thus, SDK has concluded that it has no alternative but to ask its customers to bear part of the cost increase in order to ensure the stable supply of its aluminum hydroxide and alumina.
Better results were observed by the addition of aluminum hydroxide as a 2% solution in saturated NaOH.
INCI name: titanium dioxide (and) aluminum hydroxide (and) hydrated silica (and) methicone
The tread rubber composition contains aluminum hydroxide having an untamped density of not more than 0.60 g/cm.sup.3, a DOP oil absorption of at least 70 cm.sup.3/100 g and less than 250 cm.sup.3/100 g, and a BET specific surface area of at least 30 m.sup.2/g and not more than 350 m.sup.2/g in an amount of 560 parts by weight with respect to 100 parts by weight of a rubber component containing at least 50% by weight of at least one of polyisoprene rubber and polybutadiene rubber.
Supplies Martinal specialty aluminum hydroxide and Magnifin magnesium hydroxide flame-retardant fillers, which are environmentally friendly and economical.
By treating an inexpensive, naturally occurring clay with a solution of water-soluble aluminum hydroxide, researchers at the University of Michigan in Ann Arbor have been able to modify the clay so that it binds with toxic organic chemicals, most notably 2, 3, 7, 8-TCDD, the most toxic species of dioxin.
The grades of Martinal (aluminum hydroxide specialties) and Magnifin (magnesium hydroxide specialties) flame retardants, which contain a synergist based on nano technology, are said to make it much easier for users to obtain a VO (zero) classification than with traditional mineral grades.
* Martinal aluminum hydroxide flame-retardants with a processing temperature up to 200 C.
Provides magnesium hydroxide and aluminum hydroxide flame retardants and smoke suppressants: